ArticleApplied and environmental microbiology2006
Genome sequence of the chemolithoautotrophic nitrite-oxidizing bacterium Nitrobacter winogradskyi Nb-255.
Article in Applied and environmental microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 193 citations in OpenAlex.
- Acidotolerant soil nitrite oxidizer "ISME communications · 2026Article
- Diversity of Bacteria.Progress in molecular and subcellular biology · 2026Review
- Uncovering diversity and abundance patterns of COnpj biodiversity · 2025Article
- Establishing a co-culture aggregate of N-cycle bacteria to elucidate flocculation in biological wastewater treatment.Applied microbiology and biotechnology · 2025Article
- Analysis of the Genomes and Adaptive Traits ofMicroorganisms · 2025Article
- High strain-level diversity of Bradyrhizobium across Australian soils.The ISME journal · 2025Article
- Enrichment and identification of a moderately acidophilic nitrite-oxidizing bacterium.Water research X · 2025Article
- Article
- Physiological and Genomic Characterization of Oligotrophic Nitrobacter Isolated from a Forest Soil in Japan.Microbes and environments · 2025Article
- A positive contribution to nitrogen removal by a novel NOB in a full-scale duck wastewater treatment system.Water research X · 2024Article
- Whole transcriptome analysis highlights nutrient limitation of nitrogen cycle bacteria in simulated microgravity.NPJ microgravity · 2024Article
- Complex evolutionary history of photosynthesis inMicrobial genomics · 2023Article
- Genome Streamlining, Proteorhodopsin, and Organic Nitrogen Metabolism in Freshwater Nitrifiers.mBio · 2022Article
- Biochemistry shapes growth kinetics of nitrifiers and defines their activity under specific environmental conditions.Biotechnology and bioengineering · 2022Article
- Determination ofApplied and environmental microbiology · 2022Article
- Differential Responses of the Catalytic Efficiency of Ammonia and Nitrite Oxidation to Changes in Temperature.Frontiers in microbiology · 2022Article
- Development of Nitrogen Recycling Strategies for Bioregenerative Life Support Systems in Space.Frontiers in microbiology · 2021Review
- Cultivation and Transcriptional Analysis of a CanonicalFrontiers in microbiology · 2019Article
- Genomic profiling of four cultivated Candidatus Nitrotoga spp. predicts broad metabolic potential and environmental distribution.The ISME journal · 2018Article
- Characterization of the First "mBio · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The alphaproteobacterium Nitrobacter winogradskyi (ATCC 25391) is a gram-negative facultative chemolithoautotroph capable of extracting energy from the oxidation of nitrite to nitrate. Sequencing and analysis of its genome revealed a single circular chromosome of 3,402,093 bp encoding 3,143 predicted proteins. There were extensive similarities to genes in two alphaproteobacteria, Bradyrhizobium japonicum USDA110 (1,300 genes) and Rhodopseudomonas palustris CGA009 CG (815 genes). Genes encoding pathways for known modes of chemolithotrophic and chemoorganotrophic growth were identified. Genes encoding multiple enzymes involved in anapleurotic reactions centered on C2 to C4 metabolism, including a glyoxylate bypass, were annotated. The inability of N. winogradskyi to grow on C6 molecules is consistent with the genome sequence, which lacks genes for complete Embden-Meyerhof and Entner-Doudoroff pathways, and active uptake of sugars. Two gene copies of the nitrite oxidoreductase, type I ribulose-1,5-bisphosphate carboxylase/oxygenase, cytochrome c oxidase, and gene homologs encoding an aerobic-type carbon monoxide dehydrogenase were present. Similarity of nitrite oxidoreductases to respiratory nitrate reductases was confirmed. Approximately 10% of the N. winogradskyi genome codes for genes involved in transport and secretion, including the presence of transporters for various organic-nitrogen molecules. The N. winogradskyi genome provides new insight into the phylogenetic identity and physiological capabilities of nitrite-oxidizing bacteria. The genome will serve as a model to study the cellular and molecular processes that control nitrite oxidation and its interaction with other nitrogen-cycling processes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.