Trial reportThorax2006
Double blind randomised controlled trial of two different breathing techniques in the management of asthma.
Trial report in Thorax, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05593315 (Efficacy of the Combination of General Relaxation), which is not on this map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of the Combination of General Relaxation (Mindfulness) and Respiratory (Buteyko) Techniques for the Improvement of Poorly Controlled Asthma. The MBA Study
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Breathing techniques to reduce symptoms in people with serious respiratory illness: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Breathing exercises for adults with asthma.The Cochrane database of systematic reviews · 2020Pooled it
- Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults.The Cochrane database of systematic reviews · 2013Pooled it
- Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2011Pooled it
- Effect of Buteyko breathing technique on clinical and functional parameters in adult patients with asthma: a randomized, controlled study.European journal of medical research · 2024Trial
- Trial
- Comprehensive exercise program based on optimal physiotherapy for asthma-related quality of life: a systematic review and network meta-analysis.Frontiers in sports and active living · 2025Review
- Questions in Mild Asthma: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2023Article
- Patients' experiences of breathing retraining for asthma: a qualitative process analysis of participants in the intervention arms of the BREATHE trial.NPJ primary care respiratory medicine · 2017Article
- Hypoventilation training for asthma: a case illustration.Applied psychophysiology and biofeedback · 2012Article
- Article
- The effect of various breathing exercises (pranayama) in patients with bronchial asthma of mild to moderate severity.International journal of yoga · 2009Article
- Breathing techniques in the management of asthma.Thorax · 2007Article
- Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have shown that breathing techniques reduce short acting beta(2) agonist use and improve quality of life (QoL) in asthma. The primary aim of this double blind study was to compare the effects of breathing exercises focusing on shallow nasal breathing with those of non-specific upper body exercises on asthma symptoms, QoL, other measures of disease control, and inhaled corticosteroid (ICS) dose. This study also assessed the effect of peak flow monitoring on outcomes in patients using breathing techniques.
methodsAfter a 2 week run in period, 57 subjects were randomised to one of two breathing techniques learned from instructional videos. During the following 30 weeks subjects practised their exercises twice daily and as needed for relief of symptoms. After week 16, two successive ICS downtitration steps were attempted. The primary outcome variables were QoL score and daily symptom score at week 12.
resultsOverall there were no clinically important differences between the groups in primary or secondary outcomes at weeks 12 or 28. The QoL score remained unchanged (0.7 at baseline v 0.5 at week 28, p = 0.11 both groups combined), as did lung function and airway responsiveness. However, across both groups, reliever use decreased by 86% (p<0.0001) and ICS dose was reduced by 50% (p<0.0001; p>0.10 between groups). Peak flow monitoring did not have a detrimental effect on asthma outcomes.
conclusionBreathing techniques may be useful in the management of patients with mild asthma symptoms who use a reliever frequently, but there is no evidence to favour shallow nasal breathing over non-specific upper body exercises.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.