ArticleGenome biology2006
On the evolution of the standard amino-acid alphabet.
Article in Genome biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Discovery of potent low-toxicity antimicrobial peptides through diffusion modeling.Nature communications · 2026Article
- Article
- Deciphering the conformational landscape of few selected aromatic noncoded amino acids (NCAAs) for applications in rational design of peptide therapeutics.Amino acids · 2022Article
- Improved l-phenylglycine synthesis by introducing an engineered cofactor self-sufficient system.Synthetic and systems biotechnology · 2022Article
- Protein-protein interaction prediction with deep learning: A comprehensive review.Computational and structural biotechnology journal · 2022Review
- Commentary on Urinary l-erythro-β-hydroxyasparagine: a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase.Bioscience reports · 2021Article
- Genetic engineering approaches for the fermentative production of phenylglycines.Applied microbiology and biotechnology · 2020Article
- Reconstruction of cysteine biosynthesis using engineered cysteine-free enzymes.Scientific reports · 2018Article
- Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity.Nature protocols · 2017Article
- Pathways of Genetic Code Evolution in Ancient and Modern Organisms.Journal of molecular evolution · 2015Review
- The ribosome challenge to the RNA world.Journal of molecular evolution · 2015Review
- Extraordinarily adaptive properties of the genetically encoded amino acids.Scientific reports · 2015Article
- Synthesis of constrained analogues of tryptophan.Beilstein journal of organic chemistry · 2015Article
- The amino acid alphabet and the architecture of the protein sequence-structure map. I. Binary alphabets.PLoS computational biology · 2014Article
- Cys-X scanning for expansion of active-site residues and modulation of catalytic functions in a glutathione transferase.The Journal of biological chemistry · 2011Article
- Origin and evolution of the genetic code: the universal enigma.IUBMB life · 2009Review
- Origination of the split structure of spliceosomal genes from random genetic sequences.PloS one · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although one standard amino-acid 'alphabet' is used by most organisms on Earth, the evolutionary cause(s) and significance of this alphabet remain elusive. Fresh insights into the origin of the alphabet are now emerging from disciplines as diverse as astrobiology, biochemical engineering and bioinformatics.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.