ArticleBiophysical journal2006
Theoretical analysis of single-molecule force spectroscopy experiments: heterogeneity of chemical bonds.
Article in Biophysical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Combining DNA scaffolds and acoustic force spectroscopy to characterize individual protein bonds.Biophysical journal · 2023Article
- The biophysics of bacterial infections: Adhesion events in the light of force spectroscopy.Cell surface (Amsterdam, Netherlands) · 2021Article
- Improving estimation of kinetic parameters in dynamic force spectroscopy using cluster analysis.The Journal of chemical physics · 2018Article
- Size-Dependent Affinity of Glycine and Its Short Oligomers to Pyrite Surface: A Model for Prebiotic Accumulation of Amino Acid Oligomers on a Mineral Surface.International journal of molecular sciences · 2018Article
- Directly measuring single-molecule heterogeneity using force spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Mechanical stability of bivalent transition metal complexes analyzed by single-molecule force spectroscopy.Beilstein journal of organic chemistry · 2015Article
- Two barriers or not? Dynamic force spectroscopy on the integrin α7β1 invasin complex.Biophysical journal · 2013Article
- Long lifetime of hydrogen-bonded DNA basepairs by force spectroscopy.Biophysical journal · 2012Article
- Hidden multiple bond effects in dynamic force spectroscopy.Biophysical journal · 2012Article
- Quantitative analysis of the nanopore translocation dynamics of simple structured polynucleotides.Biophysical journal · 2012Article
- Antibody-unfolding and metastable-state binding in force spectroscopy and recognition imaging.Biophysical journal · 2011Article
- Single-molecule adhesion forces and attachment lifetimes of myosin-I phosphoinositide interactions.Biophysical journal · 2010Article
- Force-induced lysozyme--HyHEL5 antibody dissociation and its analysis by means of a cooperative binding model.Biophysical journal · 2010Article
- Methods and estimations of uncertainties in single-molecule dynamic force spectroscopy.European biophysics journal : EBJ · 2009Article
- Quantitative analysis of single-molecule RNA-protein interaction.Biophysical journal · 2009Article
- Mechanically interlocked calix[4]arene dimers display reversible bond breakage under force.Nature nanotechnology · 2009Article
- Effects of multiple-bond ruptures on kinetic parameters extracted from force spectroscopy measurements: revisiting biotin-streptavidin interactions.Biophysical journal · 2008Article
- A structural, kinetic model of soft tissue thermomechanics.Biophysical journal · 2008Article
- Impact of receptor-ligand distance on adhesion cluster stability.The European physical journal. E, Soft matter · 2007Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We show that the standard theoretical framework in single-molecule force spectroscopy has to be extended to consistently describe the experimental findings. The basic amendment is to take into account heterogeneity of the chemical bonds via random variations of the force-dependent dissociation rates. This results in a very good agreement between theory and rupture data from several different experiments.
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