ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2006
Operant conditioning of gill withdrawal in Aplysia.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Direct instrumental conditioning of neural activity using functional magnetic resonance imaging-derived reward feedback.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Trial
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- Heksor: the central nervous system substrate of an adaptive behaviour.The Journal of physiology · 2022Article
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- The Yin and Yang of Sleep and Attention.Trends in neurosciences · 2015Review
- Associative learning in invertebrates.Cold Spring Harbor perspectives in biology · 2015Review
- From Affective Experience to Motivated Action: Tracking Reward-Seeking and Punishment-Avoidant Behaviour in Real-Life.PloS one · 2015Article
- Aplysia Ganglia preparation for electrophysiological and molecular analyses of single neurons.Journal of visualized experiments : JoVE · 2014Article
- Orbitofrontal reality filtering.Frontiers in behavioral neuroscience · 2013Article
- Benefit of the doubt: a new view of the role of the prefrontal cortex in executive functioning and decision making.Frontiers in neuroscience · 2013Article
- The evolutionary and genetic origins of consciousness in the Cambrian Period over 500 million years ago.Frontiers in psychology · 2013Article
- The tail-elicited tail withdrawal reflex of Aplysia is mediated centrally at tail sensory-motor synapses and exhibits sensitization across multiple temporal domains.Learning & memory (Cold Spring Harbor, N.Y.) · 2011Article
- Transcriptional regulation of long-term memory in the marine snail Aplysia.Molecular brain · 2008Review
- Behavioral and in vitro correlates of compulsive-like food seeking induced by operant conditioning in Aplysia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
- In vitro analog of operant conditioning in aplysia. I. Contingent reinforcement modifies the functional dynamics of an identified neuron.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999Article
- Neural changes after operant conditioning of the aerial respiratory behavior in Lymnaea stagnalis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999Article
- Contingent-dependent enhancement of rhythmic motor patterns: an in vitro analog of operant conditioning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997Article
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3 authors.
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Abstract
A basic question in neuroscience is how different forms of learning are related. To further address that question, we examined whether gill withdrawal in Aplysia, which has already been studied extensively for neuronal mechanisms contributing to habituation, sensitization, and classical conditioning, also undergoes operant conditioning. Animals were run in pairs. During the initial training period, the contingent (experimental) animal received a siphon shock each time its gill relaxed below a criterion level, and the yoked control animal received a shock whenever the experimental animal did, regardless of its own gill position. This was followed by an extinction period when there was no shock, a retraining period when both animals were contingent, and another extinction period. The experimental animals spent more time with their gills contracted above the criterion level than did the control animals during each period, demonstrating operant conditioning. The type of gill behavior modified by learning shifted over time: the experimental animals had a larger increase in the frequency and duration of spontaneous contractions than did the control animals during the first but not the last extinction period and a larger increase in the level of tonic contraction during the last but not the first extinction period. Because many of the neurons controlling spontaneous and tonic gill withdrawal have already been identified, it should now be possible to examine the cellular locus and mechanism of operant conditioning and compare them with those for other forms of learning of the same behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.