ArticleEnvironmental health perspectives2006
Using biologic markers in blood to assess exposure to multiple environmental chemicals for inner-city children 3-6 years of age.
Article in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- A systematic review and meta-analysis of childhood leukemia and parental occupational pesticide exposure.Environmental health perspectives · 2009Pooled it
- Evaluating the impact of environmental metal mixtures on chronic kidney disease risk: Insights from the National Health and Nutrition Examination Survey 2011-2016.The Journal of international medical research · 2025Article
- Metabolomics and the Multi-Omics View of Cancer.Metabolites · 2022Review
- Prenatal exposure to a mixture of elements and neurobehavioral outcomes in mid-childhood: Results from Project Viva.Environmental research · 2021Article
- Extrapolation of Hepatic Concentrations of Industrial Chemicals Using Pharmacokinetic Models to Predict Hepatotoxicity.Toxicological research · 2019Review
- Lead exposure during childhood and subsequent anthropometry through adolescence in girls.Environment international · 2019Article
- Perinatal and Childhood Exposure to Cadmium, Manganese, and Metal Mixtures and Effects on Cognition and Behavior: A Review of Recent Literature.Current environmental health reports · 2015Review
- The Effect of Socio-Economic-Cultural Factors on Breast Cancer.The journal of breast health · 2015Article
- Exposure assessment of organochlorine pesticides, arsenic, and lead in children from the major agricultural areas in Sonora, Mexico.Archives of environmental contamination and toxicology · 2013Article
- Causal inference considerations for endocrine disruptor research in children's health.Annual review of public health · 2013Review
- Exposure to chemical mixtures in Mexican children: high-risk scenarios.Environmental science and pollution research international · 2013Article
- Polycyclic aromatic hydrocarbons in maternal and umbilical cord blood from pregnant Hispanic women living in Brownsville, Texas.International journal of environmental research and public health · 2011Article
- Research needs for community-based risk assessment: findings from a multi-disciplinary workshop.Journal of exposure science & environmental epidemiology · 2010Article
- Childhood Development and Access to Nature: A New Direction for Environmental Inequality Research.Organization & environment · 2009Article
- Assessing cumulative health risks from exposure to environmental mixtures - three fundamental questions.Environmental health perspectives · 2007Article
- Volatile organic compounds and pulmonary function in the Third National Health and Nutrition Examination Survey, 1988-1994.Environmental health perspectives · 2006Article
- Using exposure biomarkers in children to compare between-child and within-child variance and calculate correlations among siblings for multiple environmental chemicals.Journal of exposure science & environmental epidemiologyArticle
- Developmental manganese, lead, and barren cage exposure have adverse long-term neurocognitive, behavioral and monoamine effects in Sprague-Dawley rats.Neurotoxicology and teratologyArticle
- Evaluation of NHANES biomonitoring data for volatile organic chemicals in blood: application of chemical-specific screening criteria.Journal of exposure science & environmental epidemiologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We assessed concurrent exposure to a mixture of > 50 environmental chemicals by measuring the chemicals or their metabolites in the blood of 43 ethnically diverse children (3-6 years of age) from a socioeconomically disadvantaged neighborhood in Minneapolis. Over a 2-year period, additional samples were collected every 6-12 months from as many children as possible. We analyzed blood samples for 11 volatile organic compounds (VOCs), 2 heavy metals (lead and mercury, 11 organochlorine (OC) pesticides or related compounds, and 30 polychlorinated biphenyl (PCB) congeners. The evidence suggests that numerous VOCs originated from common sources, as did many PCBs. Longitudinal measurements indicate that between-child variance was greater than within-child variance for two VOCs (benzene, toluene), for both heavy metals (Pb, Hg), for all detectable OC pesticides, and for 15 of the measured PCB congeners (74, 99, 101, 118, 138-158, 146, 153, 156, 170, 178, 180, 187, 189, 194, 195). Despite the relatively small sample size, highest measured blood levels of 1,4-dichlorobenzene, styrene, m-/p-xylene, Pb, Hg, heptachlor epoxide, oxychlordane, dichlorodiphenyldichloroethene (p,p -DDE), trans-nonachlor, and PCB congeners 74, 99, 105, 118, 138, 146, 153, 156, 170, and 180 were comparable with or higher than 95th percentile measurements of older children and adults from national surveys. Results demonstrate that cumulative exposures to multiple environmental carcinogens and neurotoxins can be comparatively high for children from a poor inner-city neighborhood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.