ArticleThe Journal of comparative neurology2006
Histamine receptors in mammalian retinas.
Article in The Journal of comparative neurology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.Journal of medicinal chemistry · 2026Article
- Amine-responsive Rhodopsin-like GPCRs in ocular pathology: mechanistic associations, candidate biomarkers, and therapeutic potential.Frontiers in physiology · 2026Review
- Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes.Investigative ophthalmology & visual science · 2025Article
- Top-down modulation of the retinal code via histaminergic neurons of the hypothalamus.Science advances · 2024Article
- Loratadine-associated cystoid macular edema: A case report.American journal of ophthalmology case reports · 2022Article
- Sex-Specific Retinal Anomalies Induced by Chronic Social Defeat Stress in Mice.Frontiers in behavioral neuroscience · 2021Article
- Role of Histamine H₃ Receptor Antagonists on Intraocular Pressure Reduction in Rabbit Models of Transient Ocular Hypertension and Glaucoma.International journal of molecular sciences · 2019Article
- Development of cone photoreceptors and their synapses in the human and monkey fovea.The Journal of comparative neurology · 2019Article
- The Effect of Histamine on Inward and Outward Currents in Mouse Retinal Amacrine Cells.Cellular and molecular neurobiology · 2018Article
- Nitric oxide promotes GABA release by activating a voltage-independent CaJournal of neurophysiology · 2017Article
- Membrane-associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors.The Journal of comparative neurology · 2017Article
- Efferent influences on the bioelectrical activity of the retina in primates.Documenta ophthalmologica. Advances in ophthalmology · 2017Review
- Wide-field diffuse amacrine cells in the monkey retina contain immunoreactive Cocaine- and Amphetamine-Regulated Transcript (CART).Peptides · 2016Article
- Involvement of histaminergic inputs in the jaw-closing reflex arc.Journal of neurophysiology · 2015Article
- Synaptic connections of amacrine cells containing vesicular glutamate transporter 3 in baboon retinas.Visual neuroscience · 2015Article
- Article
- Histamine receptors of cones and horizontal cells in Old World monkey retinas.The Journal of comparative neurology · 2012Article
- Histamine elevates free intracellular calcium in mouse retinal dopaminergic cells via H1-receptors.Investigative ophthalmology & visual science · 2011Article
- Histamine reduces flash sensitivity of on ganglion cells in the primate retina.Investigative ophthalmology & visual science · 2010Article
- Histamine enhances voltage-gated potassium currents of ON bipolar cells in macaque retina.Investigative ophthalmology & visual science · 2009Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Mammalian retinas are innervated by histaminergic axons that originate from perikarya in the posterior hypothalamus. To identify the targets of these retinopetal axons, we localized histamine receptors (HR) in monkey and rat retinas by light and electron microscopy. In monkeys, puncta containing HR3 were found at the tips of ON-bipolar cell dendrites in cone pedicles and rod spherules, closer to the photoreceptors than the other neurotransmitter receptors. This is the first ultrastructural localization of any histamine receptor and the first direct evidence that HR3 is present on postsynaptic membranes in the central nervous system. In rat retinas, most HR1 were localized to dopaminergic amacrine cells. The differences in histamine receptor localization may reflect the differences in the activity patterns of the two species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.