ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2006
Gene regulation and large-scale chromatin organization in the nucleus.
Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Mixing chromatin fibers with different nucleosome repeat lengths changes dynamics of chromatin phase separation.The Journal of biological chemistry · 2026Article
- Quantifying Nuclear Structures of Digital Pathology Images Across Cancers Using Transport-Based Morphometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2025Article
- Downregulation of PTCD1 in Bladder Urothelial Carcinoma Predicts Poor Prognosis and Levels of Immune Infiltration.Journal of oncology · 2022Article
- Methylation as a critical epigenetic process during tumor progressions among Iranian population: an overview.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021Review
- Cyproheptadine, an epigenetic modifier, exhibits anti-tumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma.Cancer cell international · 2021Article
- Epigenetic Alterations in Bladder Cancer.Current urology reports · 2018Review
- Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration.Current neuropharmacology · 2016Review
- Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers.Current topics in medicinal chemistry · 2016Review
- Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells.Molecular and cellular biology · 2013Article
- Estrogen represses gene expression through reconfiguring chromatin structures.Nucleic acids research · 2013Article
- DNA methylation pattern as important epigenetic criterion in cancer.Genetics research international · 2013Review
- The influence of DNA sequence on epigenome-induced pathologies.Epigenetics & chromatin · 2012Article
- Brain region-specific expression of Fxyd1, an Mecp2 target gene, is regulated by epigenetic mechanisms.Journal of neuroscience research · 2011Article
- Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling.Steroids · 2011Review
- Article
- Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Prediction of epigenetically regulated genes in breast cancer cell lines.BMC bioinformatics · 2010Article
- Gene positioning.Cold Spring Harbor perspectives in biology · 2010Review
- A map of open chromatin in human pancreatic islets.Nature genetics · 2010Article
- Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Regulation of gene expression involves a number of different levels of organization in the cell nucleus. The main agents of transcriptional control are the cis-acting sequences in the immediate vicinity of a gene, which combine to form the functional unit or domain. Contacts between these sequences through the formation of chromatin loops forms the most basic level of organization. The activity of functional domains is also influenced by higher order chromatin structures that impede or permit access of factors to the genes. Epigenetic modifications can maintain and propagate these active or repressive chromatin structures across large genomic regions or even entire chromosomes. There is also evidence that transcription is organized into structures called 'factories' and that this can lead to inter-chromosomal contacts between genes that have the potential to influence their regulation.
Indexed as
Identifiers
16506101What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.