ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2006
Heterochromatin assembly: a new twist on an old model.
Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Who cites it
28 citing papers in PubMed.
- The TRIP12 E3 ligase induces SWI/SNF component BRG1-β-catenin interaction to promote Wnt signaling.Nature communications · 2025Article
- Recent advancements in the role of histone acetylation dynamics to improve stress responses in plants.Molecular biology reports · 2024Review
- Recent Advances in Therapeutic Modalities Against Breast Cancer-Related Lymphedema: Future Epigenetic Landscape.Lymphatic research and biology · 2023Review
- Epigenetics in Breast Cancer Therapy-New Strategies and Future Nanomedicine Perspectives.Cancers · 2020Review
- The highly expressed methionine synthase gene of Neurospora crassa is positively regulated by its proximal heterochromatic region.Nucleic acids research · 2014Article
- Histone chaperones link histone nuclear import and chromatin assembly.Biochimica et biophysica acta · 2012Article
- Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment.The European journal of neuroscience · 2011Review
- Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring.Biological psychiatry · 2011Article
- Control of nuclear receptor function by local chromatin structure.The FEBS journal · 2011Review
- Regulation of secondary metabolism by chromatin structure and epigenetic codes.Fungal genetics and biology : FG & B · 2011Review
- Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation.Molecular cancer · 2010Review
- Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.The Journal of biological chemistry · 2010Article
- The stem cell--chromatin connection.Seminars in cell & developmental biology · 2009Review
- Differential requirement of a distal regulatory region for pre-initiation complex formation at globin gene promoters.Nucleic acids research · 2009Article
- Interaction of APC/C-E3 ligase with Swi6/HP1 and Clr4/Suv39 in heterochromatin assembly in fission yeast.The Journal of biological chemistry · 2009Article
- Epigenetic marks in the mature pollen of Quercus suber L. (Fagaceae).Sexual plant reproduction · 2009Article
- Epigenetic regulation in human brain-focus on histone lysine methylation.Biological psychiatry · 2009Review
- ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation.Autoimmunity · 2008Review
- The BRG1 transcriptional coregulator.Nuclear receptor signaling · 2008Review
- ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation.Molecular and cellular biology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The organization of eukaryotic genomes requires a harmony between efficient compaction and accessibility. This is achieved through its packaging into chromatin. Chromatin can be subdivided into two general structural and functional compartments: euchromatin and heterochromatin. Euchromatin comprises most of the expressed genome, while heterochromatin participates intimately in the production of structures such as centromeres and telomeres essential for chromosome function. Studies in the fission yeast Schizosaccharomyces pombe have begun to highlight the genetic pathways critical for the assembly and epigenetic maintenance of heterochromatin, including key roles played by the RNAi machinery, H3 lysine 9 methylation and heterochromatin protein 1 (HP1). Recent studies have also identified a novel E3 ubiquitin ligase universally required for H3 K9 methylation. Here we outline these studies and propose several models for the role of this E3 ligase in heterochromatin assembly.
Indexed as
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16506098What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.