Evidence map›Paper›PMID 16505461›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2006

What is the best evidence for determining harms of medical treatment?

Jan P Vandenbroucke

Abstract readComment
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Side effects of corticosteroids in patients with advanced cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Pooled it
  3. Pooled it
  4. Combined oral contraceptives: venous thrombosis.The Cochrane database of systematic reviews · 2014
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Review
  9. Review
  10. Article
  11. Article
  12. Defining and measuring meditation-related adverse effects in mindfulness-based programs.Clinical psychological science : a journal of the Association for Psychological Science · 2021
    Article
  13. Article
  14. Ranking evidence in substance use and addiction.The International journal on drug policy · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Clinical experience with insulin detemir in patients with type 2 diabetes from the near East countries.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Jan P VandenbrouckeDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands. j.p.vandenbroucke@lumc.nl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epidemiologic StudiesEvidence-Based MedicineRandomized Controlled Trials as TopicBiasHumansRisk

Identifiers

PMID16505461
PMCPMC1389828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.