Evidence map›Paper›PMID 16503196›Full record

ReviewInternational journal of medical microbiology : IJMM2006

Pheromone-inducible conjugation in Enterococcus faecalis: a model for the evolution of biological complexity?

Briana K Kozlowicz, Martin Dworkin, Gary M Dunny

Open access · greenAbstract readReview
In one paragraph

Review in International journal of medical microbiology : IJMM, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Microorganisms · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Physiology of the read-write genome.The Journal of physiology · 2014
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Briana K KozlowiczDepartment of Microbiology, University of Minnesota Medical School, 1460 Mayo Bldg., MMC196, 420 Delaware St., SE, Minneapolis, MN 55455, USA.
Martin Dworkin
Gary M Dunny
University of Minnesota Medical Center · US

Funding

TRAINING FOR FUTURE BIOTECHNOLOGY DEVELOPMENTT32GM008347 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHMIDT-DANNERT, CLAUDIA · 1990 to 2021
$11.0M
GENETIC FUNCTIONS OF CONJUGATIVE STREPTOCOCCAL R FACTORR01GM049530 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUNNY, GARY M · 1992 to 2014
$3.6M
Biofilms and Enterococcus faecalis BiologyR01AI058134 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUNNY, GARY M · 2005 to 2015
$3.6M
ROLE OF CELLWALL COMPONENTS IN ENTEROCOCCAL ENDOCARDITISR01HL051987 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUNNY, GARY M · 1995 to 2006
$2.1M
NHLBI NIH HHS HL51987NHLBI NIH HHS R01 HL051987NIAID NIH HHS R01 AI058134NIGMS NIH HHS GM49530NIGMS NIH HHS R01 GM049530NIGMS NIH HHS T32 GM008347NIGMS NIH HHS T32 GM08347
6 · The paper itself

Abstract

Pheromone-inducible transfer of the plasmid pCF10 in Enterococcus faecalis is regulated using a complicated network of proteins and RNAs. The plasmid itself has been assembled from parts garnered from a variety of sources, and many aspects of the system resemble a biological kluge. Recently several new functions of various pCF10 gene products that participate in regulation of plasmid transfer have been identified. The results indicate that selective pressures controlling the evolution of the plasmid have produced a highly complex regulatory network with multiple biological functions that may serve well as a model for the evolution of biological complexity.

Indexed as

Conjugation, GeneticBacterial ProteinsBiological EvolutionEnterococcus faecalisGene Transfer, HorizontalModels, BiologicalOligopeptidesPheromonesPlasmidsProtein Sorting SignalsVirulenceBacterial ProteinsiCF10 peptide precursor, Plasmid pCF10Oligopeptidespeptide pheromone cCF10PheromonesProtein Sorting Signals

Identifiers

PMID16503196
PMCPMC2664266
OpenAlexW2020693244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.