Evidence map›Paper›PMID 16501103›Full record

ArticleJournal of virology2006

Identification and characterization of an exogenous retrovirus from atlantic salmon swim bladder sarcomas.

Thomas A Paul, Sandra L Quackenbush, Claudia Sutton, Rufina N Casey, Paul R Bowser, James W Casey

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 51 citations in OpenAlex.

  1. RNAViruses · 2026
    Review
  2. Review
  3. Article
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  8. Infection and cancer in multicellular organisms.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  9. Article
  10. Article
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  12. Article
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Wildlife cancer: a conservation perspective.Nature reviews. Cancer · 2009
    Review
  20. Powerful mutators lurking in the genome.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Thomas A PaulDepartment of Microbiology and Immunology, C4137 VMC, Cornell University, Ithaca, New York 14853, USA.
Sandra L Quackenbush
Claudia Sutton
Rufina N Casey
Paul R Bowser
James W Casey
Cornell University · USColorado State University · US

Funding

TRAINING IN MOLECULAR AND CELL BIOLOGY OF CANCERT32CA009682 · NCI · CORNELL UNIVERSITY ITHACA · PI PAULI, BENDICHT U · 1992 to 2007
$1.9M
NCI NIH HHS 5T32CA09682NCI NIH HHS T32 CA009682
6 · The paper itself

Abstract

A novel piscine retrovirus has been identified in association with an outbreak of leiomyosarcoma in the swim bladders of Atlantic salmon. The complete nucleotide sequence of the Atlantic salmon swim bladder sarcoma virus (SSSV) provirus is 10.9 kb in length and shares a structure and transcriptional profile similar to those of murine leukemia virus-like simple retroviruses. SSSV appears unique to simple retroviruses by not harboring sequences in the Atlantic salmon genome. Additionally, SSSV differs from other retroviruses in potentially utilizing a methionine tRNA primer binding site. SSSV-associated tumors contain high proviral copy numbers (greater than 30 per cell) and a polyclonal integration pattern. Phylogenetic analysis based on reverse transcriptase places SSSV with zebrafish endogenous retrovirus (ZFERV) between the Gammaretrovirus and Epsilonretrovirus genera. Large regions of continuous homology between SSSV and ZFERV Gag, Pol, and Env suggest that these viruses represent a new group of related piscine retroviruses.

Indexed as

Air SacsAmino Acid SequenceAnimalsFish DiseasesLeiomyosarcomaMolecular Sequence DataPhylogenyRespiratory Tract InfectionsRetroviridaeRetroviridae InfectionsSalmo salarSequence Analysis, DNATumor Virus Infections

Identifiers

PMID16501103
PMCPMC1395439
OpenAlexW2137439223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.