ArticleProceedings of the National Academy of Sciences of the United States of America2006
Clonal population structure and genetic diversity of Candida albicans in AIDS patients from Abidjan (Côte d'Ivoire).
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 50 citations in OpenAlex.
- Mechanisms of genome evolution in Candida albicans.Current opinion in microbiology · 2019Review
- Genetic and Genome Analyses Reveal Genetically Distinct Populations of the Bee Pathogen Nosema ceranae from Thailand.Microbial ecology · 2019Article
- The Genome of the Human PathogenmBio · 2018Article
- Population Genetics and Reproductive Strategies of African Trypanosomes: Revisiting Available Published Data.PLoS neglected tropical diseases · 2015Review
- Null allele, allelic dropouts or rare sex detection in clonal organisms: simulations and application to real data sets of pathogenic microbes.Parasites & vectors · 2014Article
- Population genetics of Trypanosoma brucei circulating in Glossina palpalis palpalis and domestic animals of the Fontem sleeping sickness focus of Cameroon.Parasites & vectors · 2014Article
- Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Multifaceted population structure and reproductive strategy in Leishmania donovani complex in one Sudanese village.PLoS neglected tropical diseases · 2011Article
- Extraordinary Trypanosoma cruzi diversity within single mammalian reservoir hosts implies a mechanism of diversifying selection.International journal for parasitology · 2011Article
- MultiTest V.1.2, a program to binomially combine independent tests and performance comparison with other related methods on proportional data.BMC bioinformatics · 2009Article
- Extreme inbreeding in Leishmania braziliensis.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have investigated the genotype at 14 enzyme-encoding loci in 275 isolates of the pathogenic yeast Candida albicans sampled from 42 HIV-positive patients (all but one with AIDS) from Abidjan (Côte d'Ivoire). We separately analyzed the following variables: patient, residence, age, gender, T cell count, hospitalization (yes or no), drug treatment, date of sampling, multilocus genotype, and serotype. The most important factors contributing to the genetic variability of C. albicans are individual patient and gender. Our data manifest that the population size of the parasite is relatively small within each patient, although larger in women than in men, and that, at least for the patients involved in the study, the transmission rate of C. albicans between human adults is very low. Most important is the inference that the prevailing mode of reproduction of C. albicans in natural populations is clonal, so that sexual reproduction is extremely rare, if it occurs at all.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.