Evidence map›Paper›PMID 16500926›Full record

ArticleBMJ (Clinical research ed.)2006

Applicability to primary care of national clinical guidelines on blood pressure lowering for people with stroke: cross sectional study.

Jonathan Mant, Richard J McManus, Rachel Hare

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Primary care evidence in clinical guidelines: a mixed methods study of practitioners' views.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Multimorbidity and risk among patients with established cardiovascular disease: a cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2008
    Article
  12. How to formulate research recommendations.BMJ (Clinical research ed.) · 2006
    Review
  13. Under pressure.The British journal of general practice : the journal of the Royal College of General Practitioners · 2006
    Article
  14. Article
  15. What sort of evidence do we need in primary care?BMJ (Clinical research ed.) · 2006
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jonathan MantDepartment of Primary Care and General Practice, Primary Care, University of Birmingham, Birmingham B15 2TT. j.w.mant@bham.ac.uk
Richard J McManus
Rachel Hare

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the characteristics of patients with cerebrovascular disease in primary care with those of the participants in the PROGRESS trial, on which national guidelines for blood pressure lowering are based.

designPopulation based cross sectional survey of patients with confirmed stroke or transient ischaemic attack.

settingSeven general practices in south Birmingham, England.

participantsAll patients with a validated history of stroke (n = 413) or transient ischaemic attack (n = 107).

main outcome measuresPATIENT CHARACTERISTICS: age, sex, time since last cerebrovascular event, blood pressure, and whether receiving antihypertensive treatment.

resultsPatients were 12 years older than the participants in PROGRESS and twice as likely to be women. The median time that had elapsed since their cerebrovascular event was two and a half years, compared with eight months in PROGRESS. The systolic blood pressure of 315 (61%) patients was over 140 mm Hg, and for 399 (77%) it was over 130 mm Hg. One hundred and forty seven (28%) patients were receiving a thiazide diuretic, and 136 (26%) were receiving an angiotensin converting enzyme inhibitor.

conclusionsImportant differences exist between the PROGRESS trial participants and a typical primary care stroke population, which undermine the applicability of the trial's findings. Research in appropriate populations is urgently needed before the international guidelines are implemented in primary care.

Indexed as

Practice Guidelines as TopicAgedBlood PressureCross-Sectional StudiesEnglandFamily PracticeFemaleHumansHypertensionMaleStroke

Identifiers

PMID16500926
PMCPMC1403277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.