SynthesisEmergency medicine journal : EMJ2006
Diagnosis of pulmonary embolism with CT pulmonary angiography: a systematic review.
Synthesis in Emergency medicine journal : EMJ, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Pooled it
- Design-related bias in studies investigating diagnostic tests for venous thromboembolic diseases: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Time efficiency and reliability of established computed tomographic obstruction scores in patients with acute pulmonary embolism.PloS one · 2021Trial
- Deep vein thrombosis and coagulopathy following cyclone events: pathophysiology, risk factors, and prevention.Annals of medicine and surgery (2012) · 2026Review
- Computed tomography pulmonary angiography in around-the-clock clinical care with individualised scan protocols: a 5-year observational study on incidence and causes of repeat scanning.European radiology · 2026Observational
- Diagnostic Performance of Quantitative Computed Tomography Pulmonary Angiography Parameters in Patients With Pulmonary Embolism.Pulmonary medicine · 2025Article
- Improved detection of small pulmonary embolism on unenhanced computed tomography using an artificial intelligence-based algorithm - a single centre retrospective study.The international journal of cardiovascular imaging · 2024Article
- Article
- Evolving paradigm of thrombolysis in pulmonary embolism: Comprehensive review of clinical manifestations, indications, recent advances and guideline.World journal of clinical cases · 2023Review
- A 60-Year-Old Woman with a 6-Week History of Shortness of Breath and Intermittent Chest Pain Due to Chronic Thromboembolic Pulmonary Disease Undetected by Computed Tomography Pulmonary Angiography (CTPA) and Diagnosed by Ventilation-Perfusion Imaging.The American journal of case reports · 2022Article
- Early post-traumatic pulmonary embolism in intensive care unit: incidence, risks factors, and impact outcome.American journal of cardiovascular disease · 2020Article
- Rethinking Intravenous Catheter Size and Location for Computed Tomography Pulmonary Angiography.The western journal of emergency medicine · 2019Article
- Incidental Findings of Computed Tomography Angiography in Patients Suspected to Pulmonary Embolism; a Brief Report.Archives of academic emergency medicine · 2019Article
- Ruling out Pulmonary Embolism in Patients with High Pretest Probability.The western journal of emergency medicine · 2018Observational
- The Economic Value of Hybrid Single-photon Emission Computed Tomography With Computed Tomography Imaging in Pulmonary Embolism Diagnosis.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2017Article
- Dyspnoea in a young woman: the opposite of every truth is just as true.Internal and emergency medicine · 2016Article
- Paradoxical embolus straddling patent foramen ovale demonstrated by computed tomographic pulmonary angiography.World journal of clinical cases · 2013Article
- Optimisation of contrast medium volume and injection-related factors in CT pulmonary angiography: 64-slice CT study.European radiology · 2010Article
- Computed tomography pulmonary angiography: a sample of experience at a District General Hospital.The Ulster medical journal · 2008Article
- Review of the evidence on diagnosis of deep venous thrombosis and pulmonary embolism.Annals of family medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo appraise the evidence on the diagnostic accuracy of CT pulmonary angiography and the prognostic value of a negative CT pulmonary angiogram in the diagnosis of pulmonary embolism.
methodsMedline, EMBASE, and grey literature were systematically searched by two researchers. Any study which compared CT pulmonary angiography to an acceptable reference standard or prospectively followed up a cohort of patients with a normal CT pulmonary angiogram was included. Study methods were appraised independently by two researchers, and data were extracted independently by three researchers.
resultsThirteen diagnostic and 11 follow up studies were identified. Studies varied in prevalence of pulmonary embolism (19-79%), patient groups, and method quality. Few studies recruited unselected emergency department patients. There was heterogeneity in the analysis of sensitivity (53 to 100%), specificity (79 to 100%), and false negative rate (1.0 to 10.7%). The pooled false negative rate of combined negative CT pulmonary angiography and negative deep vein thrombosis testing was 1.5% (95% CI 1.0 to 1.9%).
conclusionDiagnostic studies give conflicting results for the diagnostic accuracy of CT pulmonary angiography. Follow up studies show that CT pulmonary angiography can be used in combination with investigation for deep vein thrombosis to exclude pulmonary embolism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.