ReviewHormones and behavior2006
The regulation of neuroendocrine function: Timing is everything.
Review in Hormones and behavior, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 145 citations in OpenAlex.
- Daily rhythms modulate Acinetobacter baumannii physiology impacting infection outcome and antibiotic-inactivating capacity.Scientific reports · 2026Article
- Stress-Induced Hyperprolactinemia Mimicking Pituitary Pathology: A Diagnostic Challenge.Cureus · 2025Article
- Orchiectomy Decreases Locomotor Activity and Delays the Expression of the Clock Protein PER1 in the Suprachiasmatic Nucleus in Rabbits.Animals : an open access journal from MDPI · 2024Article
- Connecting the Dots: Potential Interactions Between Sex Hormones and the Circadian System During Memory Consolidation.Journal of biological rhythms · 2023Article
- The role of the circadian rhythms in critical illness with a focus on acute pancreatitis.Heliyon · 2023Review
- Review
- Disruption of Sleep Continuity During the Perimenopause: Associations with Female Reproductive Hormone Profiles.The Journal of clinical endocrinology and metabolism · 2022Article
- Morphofunctional State and Circadian Rhythms of the Liver of Female Rats under the Influence of Chronic Alcohol Intoxication and Constant Lighting.International journal of molecular sciences · 2022Article
- Sex Differences in Circadian Rhythms.Cold Spring Harbor perspectives in biology · 2022Review
- Sex differences in daily timekeeping and circadian clock circuits.Seminars in cell & developmental biology · 2022Review
- Estrogens and the circadian system.Seminars in cell & developmental biology · 2022Review
- SynGAP is expressed in the murine suprachiasmatic nucleus and regulates circadian-gated locomotor activity and light-entrainment capacity.The European journal of neuroscience · 2021Article
- Shiftwork and Light at Night Negatively Impact Molecular and Endocrine Timekeeping in the Female Reproductive Axis in Humans and Rodents.International journal of molecular sciences · 2020Review
- Oxytocinergic Cells of the Hypothalamic Paraventricular Nucleus Are Involved in Food Entrainment.Frontiers in neuroscience · 2020Article
- The My-T study: Patient satisfaction and preference comparing topical and nasal testosterone therapies.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2019Article
- MY-T study: Symptom-based titration decisions when using testosterone nasal gel, NatestoCanadian Urological Association journal = Journal de l'Association des urologues du Canada · 2019Article
- Neurogenetic basis for circadian regulation of metabolism by the hypothalamus.Genes & development · 2019Review
- Circadian Rhythms and Measures of CNS/Autonomic Interaction.International journal of environmental research and public health · 2019Review
- Energy Medicine: Current Status and Future Perspectives.Global advances in health and medicine · 2019Article
- Rhythms in the endocrine system of fish: a review.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Hormone secretion is highly organized temporally, achieving optimal biological functioning and health. The master clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus coordinates the timing of circadian rhythms, including daily control of hormone secretion. In the brain, the SCN drives hormone secretion. In some instances, SCN neurons make direct synaptic connections with neurosecretory neurons. In other instances, SCN signals set the phase of "clock genes" that regulate circadian function at the cellular level within neurosecretory cells. The protein products of these clock genes can also exert direct transcriptional control over neuroendocrine releasing factors. Clock genes and proteins are also expressed in peripheral endocrine organs providing additional modes of temporal control. Finally, the SCN signals endocrine glands via the autonomic nervous system, allowing for rapid regulation via multisynaptic pathways. Thus, the circadian system achieves temporal regulation of endocrine function by a combination of genetic, cellular, and neural regulatory mechanisms to ensure that each response occurs in its correct temporal niche. The availability of tools to assess the phase of molecular/cellular clocks and of powerful tract tracing methods to assess connections between "clock cells" and their targets provides an opportunity to examine circadian-controlled aspects of neurosecretion, in the search for general principles by which the endocrine system is organized.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.