Evidence map›Paper›PMID 16495944›Full record

ReviewNature reviews. Neuroscience2006

Looking for inspiration: new perspectives on respiratory rhythm.

Jack L Feldman, Christopher A Del Negro

Abstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 363 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
363citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

363 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Respiratory impairment and the aging lung: a novel paradigm for assessing pulmonary function.The journals of gerontology. Series A, Biological sciences and medical sciences · 2012
    Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
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  13. Biased Signaling in Psychedelic Action.Annual review of pharmacology and toxicology · 2026
    Review
  14. Review
  15. Article
  16. Review
  17. Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  18. Control of breathing during hibernation in golden-mantled ground squirrels.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025
    Article
  19. Review
  20. Review

303 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jack L FeldmanDepartment of Neurobiology, David Geffen School of Medicine at the University of California, Los Angeles, BOX 951763, Los Angeles, California 90095-1763, USA. feldman@ucla.edu
Christopher A Del Negro

Funding

RESPIRATORY PATTERN GENERATION STUDIED IN VITROR01HL040959 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FELDMAN, JACK L · 1988 to 2016
$5.9M
Generation of Respiratory RhythmR01HL070029 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FELDMAN, JACK L · 2003 to 2016
$5.4M
NHLBI NIH HHS R01 HL040959NHLBI NIH HHS R01 HL070029
6 · The paper itself

Abstract

Recent experiments in vivo and in vitro have advanced our understanding of the sites and mechanisms involved in mammalian respiratory rhythm generation. Here we evaluate and interpret the new evidence for two separate brainstem respiratory oscillators and for the essential role of emergent network properties in rhythm generation. Lesion studies suggest that respiratory cell death might explain morbidity and mortality associated with neurodegenerative disorders and ageing.

Indexed as

RespirationRespiratory Physiological PhenomenaRespiratory SystemAnimalsBiological ClocksHumansModels, BiologicalRespiratory Center

Identifiers

PMID16495944
PMCPMC2819067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.