Evidence map›Paper›PMID 16495694›Full record

Trial reportAnnals of surgery2006

Improvement of delayed gastric emptying in pylorus-preserving pancreaticoduodenectomy: results of a prospective, randomized, controlled trial.

Masaji Tani, Hiroshi Terasawa, Manabu Kawai, Shinomi Ina, Seiko Hirono, Kazuhisa Uchiyama, Hiroki Yamaue

4 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Annals of surgery, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 103 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 9 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00628186 nacompletednot on this map

Prospective, Randomized, and Controlled Trial That Lost Stent Versus External Stent of Pancreaticojejunostomy After Pancreaticoduodenectomy

TypeinterventionalSponsorWakayama Medical UniversityRan2005 to 2008Enrolled100ConditionsPancreatic Cancer, Bile Duct Cancer, Ampullary Cancer, PancreatitisArmsexternal drainage tube [polyethylene pancreatic drainage tube], internal drainage tube [polyethylene pancreatic drainage tube]
NCT00639314 nacompletednot on this map

Randomized Controlled Trial on the Evaluation of Pylorus-ring in Pancreaticoduodenectomy

TypeinterventionalSponsorWakayama Medical UniversityRan2005 to 2011Enrolled130ConditionsPancreatic Cancer, Bile Duct Cancer, Ampullary Cancer, Duodenal CancerArmspylorus-preserving pancreaticoduodenectomy, pylorus-resecting pancreaticoduodenectomy
NCT00915863 naunknown statusnot on this mapstarted 2009, after this paper: background citation

A Prospective Randomized Controlled Trial Comparing Isolated Roux-en-Y Reconstruction With Billroth-II-type Reconstruction After Pancreaticoduodenectomy

TypeinterventionalSponsorWakayama Medical UniversityRan2009 to 2014Enrolled150ConditionsPancreatic Neoplasms, Bile Duct Neoplasms, Ampullary Neoplasms, Duodenal NeoplasmsArmsBillroth-II-type reconstruction, Isolated Roux-en-Y type reconstruction
NCT01460550 phase3unknown statusnot on this mapstarted 2011, after this paper: background citation

Comparison Between Antecolic and Retrocolic Gastrointestinal Reconstruction in Delayed Gastric Emptying After Pancreaticoduodenectomy: A Prospective Randomized Controlled Multicenter Trial

TypeinterventionalSponsorKobe UniversityRan2011 to 2017Enrolled240ConditionsPostprocedural Delayed Gastric EmptyingArmsRetrocolic gastro- or duodeno- jejunostomy in hte pancreaticoduodenectomy, Antecolic gastro- or duodeno- jejunostomy in the pancreaticoduodenectomy
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 9 syntheses or guidelines pooled it, 290 citations in OpenAlex.

  1. Pooled it
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  5. Effect of Billroth II or Roux-en-Y Reconstruction for the Gastrojejunostomy After Pancreaticoduodenectomy: Meta-analysis of Randomized Controlled Trials.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
    Pooled it
  6. Pooled it
  7. Meta-analysis of antecolic versus retrocolic gastric reconstruction after a pylorus-preserving pancreatoduodenectomy.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015
    Pooled it
  8. Guideline
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  13. Delayed Gastric Emptying After Stapled Versus Hand-Sewn Anastomosis of Duodenojejunostomy in Pylorus-Preserving Pancreaticoduodenectomy: a Randomized Controlled trial.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016
    Trial
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  18. The flow angle beneath the gastrojejunostomy predicts delayed gastric emptying in Roux-en-Y reconstruction after distal gastrectomy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2012
    Trial
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  20. Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Masaji TaniSecond Department of Surgery, Wakayama Medical University, School of Medicine, Wakayama, Japan.
Hiroshi Terasawa
Manabu Kawai
Shinomi Ina
Seiko Hirono
Kazuhisa Uchiyama
Hiroki Yamaue
Wakayama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if an antecolic or a retrocolic duodenojejunostomy during pylorus-preserving pancreaticoduodenectomy (PpPD) was associated with the least incidence of delayed gastric emptying (DGE), in a prospective, randomized, controlled trial. SUMMARY BACKGROUND DATA: The pathogenesis of DGE after PpPD has been speculated to be related to factors such as inflammation, ischemia, gastric atony, motilin levels, and type of surgical procedure. Previous retrospective studies have shown a lower incidence of DGE after antecolic duodenojejunostomy. A prospective trial is needed.

methodsForty patients were enrolled in this trial between May 2002 and April 2004. Just before duodenojejunostomy during PpPD, the patients were randomly assigned to undergo either an antecolic or a retrocolic duodenojejunostomy.

resultsDGE occurred in 5% of patients with the antecolic route for duodenojejunostomy versus 50% with the retrocolic route (P = 0.0014). Those with the antecolic route had a significantly shorter duration of postoperative nasogastric tube drainage than did those with the retrocolic route (4.2 days versus 18.9 days, respectively, P = 0.047). By postoperative day 14, all patients with the antecolic route could take solid foods, while only 55% (11 of 20) of the patients with the retrocolic route could take solid foods (P = 0.0007). The length of stay in the hospital was 28 days for the antecolic group versus 48 days for the retrocolic group (P = 0.018).

conclusionsAntecolic reconstruction for duodenojejunostomy during PpPD decreases postoperative morbidity and length of hospital stay by decreasing DGE. Our data suggest that PpPD with antecolic duodenojejunostomy is a safer operation.

Indexed as

PancreaticoduodenectomyAgedBile Duct DiseasesFemaleFollow-Up StudiesGastric EmptyingHumansIncidenceMaleMiddle AgedPancreatic DiseasesProspective StudiesPylorusStomach DiseasesTreatment Outcome

Identifiers

PMID16495694
PMCPMC1448934
OpenAlexW2082161010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.