Evidence map›Paper›PMID 16494759›Full record

ArticleEmerging infectious diseases2006

Rotavirus and severe childhood diarrhea.

Umesh D Parashar, Christopher J Gibson, Joseph S Bresee, Roger I Glass

Registry-linked trialAbstract read
In one paragraph

Article in Emerging infectious diseases, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00767364 (Safety and Immunogenicity of Rotavirus Vaccine), which is not on this map. Cited by 444 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
444citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00767364 phase1completednot on this mapstarted 2009, after this paper: background citation

Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome: A Pilot Study

TypeinterventionalSponsorChildren's Hospital of MichiganRan2009 to 2013Enrolled8ConditionsShort Bowel SyndromeArmsOral, live, pentavalent rotavirus vaccine, RotaTeq(R)
3 · Its place in the literature

Who cites it

444 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Risk of Intussusception After Rotavirus Vaccination.Deutsches Arzteblatt international · 2017
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  5. [Therapeutic effects of zinc supplement as adjunctive therapy in infants and young children with rotavirus enteritis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016
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384 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Umesh D ParasharCenters for Disease Control and Prevention, Atlanta, Georgia 30333, USA. uap2@cdc.gov
Christopher J Gibson
Joseph S Bresee
Roger I Glass

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies published between 1986 and 1999 indicated that rotavirus causes approximately 22% (range 17%-28%) of childhood diarrhea hospitalizations. From 2000 to 2004, this proportion increased to 39% (range 29%-45%). Application of this proportion to the recent World Health Organization estimates of diarrhea-related childhood deaths gave an estimated 611,000 (range 454,000-705,000) rotavirus-related deaths.

Indexed as

RotavirusChildChild, PreschoolDiarrheaGlobal HealthHospitalizationHumansInfantInfant, NewbornRotavirus InfectionsSeverity of Illness IndexSocial Class

Identifiers

PMID16494759
PMCPMC3373114

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.