Evidence map›Paper›PMID 16492810›Full record

ReviewThe Journal of cell biology2006

A +TIP for a smooth trip.

Xin Xiang

Abstract readReview
In one paragraph

Review in The Journal of cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Xin XiangDepartment of Biochemistry and Molecular Biology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. xxiang@usuhs.mil

Funding

In vivo Regulation of Cytoplasmic DyneinR01GM069527 · NIGMS · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI XIANG, XIN · 2004 to 2009
$1.0M
NIGMS NIH HHS R01 GM069527
6 · The paper itself

Abstract

Is there a cellular mechanism for preventing a depolymerizing microtubule track from "slipping out from under" its cargo? A recent study in budding yeast indicates that when a chromosome is transported to the minus end of a spindle microtubule, its kinetochore-bound microtubule plus end-tracking protein (+TIP) Stu2 may move to the plus end to promote rescue; i.e., to switch the depolymerizing end to a polymerizing end. The possibility that other +TIPs may play a similar role in sustaining a microtubule track during vesicular transport deserves investigation.

Indexed as

AnimalsBiological Transport, ActiveMicrotubule-Associated ProteinsMicrotubule ProteinsMolecular Motor ProteinsNeoplasm ProteinsSaccharomyces cerevisiae Proteinscytoplasmic linker protein 170Microtubule-Associated ProteinsMicrotubule ProteinsMolecular Motor ProteinsNeoplasm ProteinsSaccharomyces cerevisiae ProteinsSTU2 protein, S cerevisiae

Identifiers

PMID16492810
PMCPMC2063697

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.