ArticleAnnals of emergency medicine2006
Validation of syndromic surveillance for respiratory infections.
Article in Annals of emergency medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Progress in Biomedical Knowledge Discovery: A 25-year Retrospective.Yearbook of medical informatics · 2016Pooled it
- Syndromic surveillance for influenza in the emergency department-A systematic review.PloS one · 2013Pooled it
- A test of syndromic surveillance using a severe acute respiratory syndrome model.The American journal of emergency medicine · 2009Trial
- Beyond influenza-like-illness: data-driven syndromic surveillance for fine-scale monitoring of seasonal respiratory viruses.medRxiv : the preprint server for health sciences · 2026Article
- Observational
- Evaluating multi-purpose syndromic surveillance systems - a complex problem.Online journal of public health informatics · 2021Article
- Ambulance dispatch calls attributable to influenza A and other common respiratory viruses in the Netherlands (2014-2016).Influenza and other respiratory viruses · 2020Article
- Article
- Article
- Influenza-like illness-related emergency department visits: Christmas and New Year holiday peaks and relationships with laboratory-confirmed respiratory virus detections, Edmonton, Alberta, 2004-2014.Influenza and other respiratory viruses · 2017Article
- A cost-effectiveness analysis of three components of a syndromic surveillance system for the early warning of epidemics in rural China.BMC public health · 2015Article
- Laboratory surveillance of influenza-like illness in seven teaching hospitals, South Korea: 2011-2012 season.PloS one · 2013Article
- Emergency department surveillance as a proxy for the prediction of circulating respiratory viral disease in Eastern Ontario.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2013Article
- Evaluating the New York City Emergency Department Syndromic Surveillance for Monitoring Influenza Activity during the 2009-10 Influenza Season.PLoS currents · 2012Article
- [Syndromic surveillance of Influenza-like illness in primary care: a complement to the sentinel surveillance network for periods of increased incidence of Influenza].Atencion primaria · 2012Article
- Effect of expanded US recommendations for seasonal influenza vaccination: comparison of two pediatric emergency departments in the United States and Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011Article
- Can near real-time monitoring of emergency department diagnoses facilitate early response to sporadic meningococcal infection?--prospective and retrospective evaluations.BMC infectious diseases · 2010Article
- Combining free text and structured electronic medical record entries to detect acute respiratory infections.PloS one · 2010Article
- Assessment of a syndromic surveillance system based on morbidity data: results from the Oscour network during a heat wave.PloS one · 2010Article
- Emergency department chief complaint and diagnosis data to detect influenza-like illness with an electronic medical record.The western journal of emergency medicine · 2010Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
STUDY
objectiveA key public health question is whether syndromic surveillance data provide early warning of infectious outbreaks. One cause for skepticism is that biological correlates of the administrative and clinical data used in these systems have not been rigorously assessed. This study measures the value of respiratory data currently used in syndromic surveillance systems to detect respiratory infections by comparing it against criterion standard viral testing within a pediatric population.
methodsWe conducted a longitudinal study with prospective validation in the emergency department (ED) of a tertiary care children's hospital. Children aged 7 years or younger who presented with a respiratory syndrome or who were tested for respiratory syncytial virus (RSV), influenza virus, parainfluenza virus, adenovirus, or enterovirus between January 1993 and June 2004 were included. We assessed the predictive ability of the viral tests by fitting generalized linear models to respiratory syndrome counts.
resultsOf 582,635 patient visits, 89,432 (15.4%) were for respiratory syndromes, and of these, 7,206 (8.1%) patients were tested for the viruses of interest. RSV was significantly related to respiratory syndrome counts (adjusted rate ratio [RR] 1.33; 95% confidence interval [CI] 1.04 to 1.71). In multivariate models including all viruses tested, influenza virus was also a significant predictor of respiratory syndrome counts (RR 1.47; 95% CI 1.03 to 2.10). This model accounted for 81.6% of the observed variability in respiratory syndrome counts.
conclusionRespiratory syndromic surveillance data strongly correlate with virologic test results in a pediatric population, providing evidence of the biologic validity of such surveillance systems. Real-time outbreak detection systems relying on syndromic data may be an important adjunct to the current set of public health systems for the detection and surveillance of respiratory infections.
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