ArticleEuropean journal of nuclear medicine and molecular imaging2006
The presentation of malignant tumours and pre-malignant lesions incidentally found on PET-CT.
Article in European journal of nuclear medicine and molecular imaging, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and Significance of Incidental PET/CT Findings of Cancer Detected in Patients Evaluated for Their Primary Hematologic Malignancy: A Systematic Review.Current oncology (Toronto, Ont.) · 2024Pooled it
- Incidental findings in imaging diagnostic tests: a systematic review.The British journal of radiology · 2010Pooled it
- Returning Incidental Research Findings FromArthritis care & research · 2024Article
- The effect of butylscopolamine on [EJNMMI research · 2023Article
- Synchronous Malignancies Identified by PET-CT Scan in Breast Cancer Patients.Rambam Maimonides medical journal · 2022Article
- Incidental analWorld journal of clinical cases · 2020Article
- The added benefit of contrast-enhanced CT in evaluation of incidental FDG-avid colon lesions.European journal of nuclear medicine and molecular imaging · 2020Article
- Reply to Letter to the Editor: "The added benefit of contrast-enhanced CT in the evaluation of incidental FDG-avid colon lesions".European journal of nuclear medicine and molecular imaging · 2020Article
- IncidentalEuropean journal of nuclear medicine and molecular imaging · 2020Article
- Triple Metachronous Malignancies with Thyroid Involvement: A Brief Overview of Five Case Reports over 20 Years of Institutional Experience.Diagnostics (Basel, Switzerland) · 2020Article
- [Importance of FDG-PET/computed tomography in colorectal cancer].Der Radiologe · 2019Review
- Incidental colorectal focalEndoscopy international open · 2017Article
- Clinical significance of incidental [18 F]FDG uptake in the gastrointestinal tract on PET/CT imaging: a retrospective cohort study.BMC gastroenterology · 2016Article
- Unfolding the role of PET FDG scan in the management of thyroid incidentaloma in cancer patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2015Article
- Incidence and Significance of Incidental Focal Thyroid Uptake on (18)F-FDG PET Study in a Large Patient Cohort: Retrospective Single-Centre Experience in the United Kingdom.European thyroid journal · 2015Article
- Clinical significance of incidental FDG uptake in the prostate gland detected by PET/CT.International journal of clinical and experimental medicine · 2015Article
- ¹⁸F-FDG uptake as a prognostic variable in primary differentiated thyroid cancer incidentally detected by PET/CT: a multicentre study.European journal of nuclear medicine and molecular imaging · 2014Article
- Prevalence and malignancy risk of focal colorectal incidental uptake detected by (18)F-FDG-PET or PET/CT: a meta-analysis.Radiology and oncology · 2014Review
- F18-FDG-PET/CT thyroid incidentalomas: a wide retrospective analysis in three Italian centres on the significance of focal uptake and SUV value.Endocrine · 2013Article
- Etiology and significance of incidentally detected focal colonic uptake on FDG PET/CT.The Indian journal of radiology & imaging · 2012Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of the study was to determine the general and organ-specific presentation of incidental primary tumours on PET-CT.
methodsPET-CT reports of 2,360 consecutive patients were reviewed and revealed 156 lesions suspicious for a new unexpected malignancy, in 151 patients. One hundred and twenty of these lesions, in 115 patients, were further assessed, by biopsy (n=84 patients) or by clinical and imaging follow-up (n=31 patients) for a mean of 17+/-4 months (range 12-25 months).
resultsForty-four unexpected malignancies were found in 41 of the study patients (1.7%). Twenty-seven of the 44 incidental tumours were identified on the basis of their location, which was uncommon for metastasis of the known malignancy. Eight were detected as a result of either the difference in FDG avidity of the known malignancy and the incidental lesion or the presence of an incidental non-FDG-avid mass on the CT part of the study. Four tumours were synchronous carcinomas in patients with known colorectal malignancy, three were identified by virtue of the discordant response to treatment compared with the known primary tumour and two were detected as new sites of disease after a prolonged disease-free period. There was organ variability in the positive predictive values (PPV) of PET-CT findings for incidental primary malignancy or pre-malignant lesions: 62% for colonic lesions, 54% for lung lesions and 24% for thyroid lesions.
conclusionIncidental primary tumours may be identified on PET-CT based on their location, FDG avidity, response to therapy and time of appearance. The PET and CT parts of the study appear to complement each other and assist in identification of these incidental tumours.
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