Evidence map›Paper›PMID 16490130›Full record

ArticleEpidemiology and infection2006

Cellular immune response to pulmonary infections in HIV-infected individuals hospitalized with diverse grades of immunosuppression.

M J Miguez-Burbano, D Ashkin, A Rodriguez, R Duncan, M Flores, B Acosta, N Quintero, A Pitchenik

Abstract read
In one paragraph

Article in Epidemiology and infection, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M J Miguez-BurbanoDivision of Disease Prevention, Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Miami, FL 33136, USA. mmiguez@med.miami.edu
D Ashkin
A Rodriguez
R Duncan
M Flores
B Acosta
N Quintero
A Pitchenik

Funding

OPTIMIZING HIV/TB MANAGEMENT IN THE HAART ERAD43TW000017 · FIC · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SHOR-POSNER, GAIL · 1988 to 2009
$4.3M
FIC NIH HHS 2D43TW00017FIC NIH HHS D43 TW000017
6 · The paper itself

Abstract

The lymphocyte profile of 521 HIV-infected subjects hospitalized at Jackson Memorial (2001-2002) was compared across main respiratory diseases. Study data included medical history and all laboratory evaluations performed during hospitalization. Community-acquired pneumonias (CAP, 52%), Pneumocystis jiroveci pneumonia (PCP, 24%), tuberculosis (TB, 9%) and non-tuberculous mycobacterial diseases (NTM, 12%) were the most frequent causes of admission. Patients hospitalized with PCP and NTM exhibited the lowest CD4 counts (P=0.003). PCP patients had the highest B-cell percentages (P=0.04). CAP patients had the highest CD8 and CD4 percentages and the lowest percentage of Natural Killer (NK) cells and viral burdens. TB patients exhibited the lowest NK-cell (11.4+/-6.3) and B-cell percentages (13.6+/-12) and the highest CD8 (59+/-14) percentage. NTM patients, in contrast, had the highest NK-cell percentages of the groups (19.1+/-11.6, P=0.01). Additionally, immune responses associated with respiratory pathogens differed in HIV-infected patients with CD4(+) cells above and below 200 counts.

Indexed as

Immunity, CellularImmunocompromised HostKiller Cells, NaturalAdultCD4-Positive T-LymphocytesCommunity-Acquired InfectionsCross-Sectional StudiesFemaleHIV InfectionsHumansInpatientsLymphocyte CountMaleMiddle AgedPatient AdmissionPneumocystis carinii

Identifiers

PMID16490130
PMCPMC2870395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.