Evidence map›Paper›PMID 16490129›Full record

ArticleEpidemiology and infection2006

Molecular epidemiology of long-term colonization of Candida albicans strains from HIV-infected patients.

S Y Li, Y L Yang, K W Chen, H H Cheng, C S Chiou, T H Wang, T L Lauderdale, C C Hung, H J Lo

Abstract read
In one paragraph

Article in Epidemiology and infection, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Frontiers in microbiology · 2018
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

S Y LiDivision of Laboratory Research and Development, Center for Disease Control, Taipei, Taiwan, ROC.
Y L Yang
K W Chen
H H Cheng
C S Chiou
T H Wang
T L Lauderdale
C C Hung
H J Lo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty-one Candida albicans isolates from three HIV-infected patients were collected over a period of 3 years and characterized for fluconazole susceptibility, infectivity and genetic relatedness. Fluconazole resistance was found in five isolates, four exhibited dose-dependent susceptibility and the remainder were fully susceptible to this agent. Pulsed-field gel electrophoresis of SfiI restriction digests of the genomic DNA from the isolates revealed that isolates from the same swab specimen were identical despite differences in susceptibility to fluconazole and isolates recovered over time from the three patients retained clonally related DNA fingerprints within each patient. This small-scale study confirms the persistence of oral colonization of C. albicans strains in HIV-infected patients. Clinical data also suggests that the primary infecting strain may become a persistent colonist in the oral cavity once the immune function of the patient has been restored.

Indexed as

AdultAntifungal AgentsCandida albicansCandidiasis, OralDNA FingerprintingDrug Resistance, BacterialFemaleFluconazoleHIV InfectionsHumansImmunocompromised HostMaleMiddle AgedMolecular EpidemiologyAntifungal AgentsFluconazole

Identifiers

PMID16490129
PMCPMC2870383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.