Evidence map›Paper›PMID 16489633›Full record

ReviewWorld journal of gastroenterology2006

Epidemiology of gastric cancer.

Katherine D Crew, Alfred I Neugut

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 784 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
784citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01961791 completednot on this map

Lymph Node Staging System With a Novel Concept for Gastric Cancer: a Hybrid Type of Topographic and Numeric Ones

TypeobservationalSponsorYonsei UniversityRan2000 to 2013Enrolled6,025ConditionsGastrectomy for Gastric CancerArmsgastrectomy
NCT06149923 unknown statusnot on this mapstarted 2023, after this paper: background citation

Association Between ABO Polymorphism and Gastric/Colorectal Cancers

TypeobservationalSponsorAssiut UniversityRan2023 to 2026Enrolled184ConditionsGastric Cancer, Colo-rectal CancerArmsquantitative Real-time PCR
3 · Its place in the literature

Who cites it

784 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  12. Trial
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  14. Multicenter prospective trial of total gastrectomy versus proximal gastrectomy for upper third cT1 gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
    Trial
  15. Trial
  16. Article
  17. Hospital-based gastric cancer outcomes in the United States (2003-2022): racial and regional disparities.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  18. Genes · 2026
    Review
  19. Article
  20. Setting a Standard for Helicobacter pylori Management in Pakistan.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Article

724 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katherine D CrewDepartment of Medicine and the Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, New York, NY 10032, United States.
Alfred I Neugut

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence and mortality of gastric cancer have fallen dramatically in US and elsewhere over the past several decades. Nonetheless, gastric cancer remains a major public health issue as the fourth most common cancer and the second leading cause of cancer death worldwide. Demographic trends differ by tumor location and histology. While there has been a marked decline in distal, intestinal type gastric cancers, the incidence of proximal, diffuse type adenocarcinomas of the gastric cardia has been increasing, particularly in the Western countries. Incidence by tumor sub-site also varies widely based on geographic location, race, and socio-economic status. Distal gastric cancer predominates in developing countries, among blacks, and in lower socio-economic groups, whereas proximal tumors are more common in developed countries, among whites, and in higher socio-economic classes. Diverging trends in the incidence of gastric cancer by tumor location suggest that they may represent two diseases with different etiologies. The main risk factors for distal gastric cancer include Helicobacter pylori (H pylori) infection and dietary factors, whereas gastroesophageal reflux disease and obesity play important roles in the development of proximal stomach cancer. The purpose of this review is to examine the epidemiology and risk factors of gastric cancer, and to discuss strategies for primary prevention.

Indexed as

DietHelicobacter InfectionsHumansMass ScreeningRisk FactorsStomach NeoplasmsSurvival Rate

Identifiers

PMID16489633
PMCPMC4066052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.