ArticleDevelopment genes and evolution2006
Expression of a muscle determinant gene, macho-1, in the anural ascidian Molgula tectiformis.
Article in Development genes and evolution, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 citing papers in PubMed, 15 citations in OpenAlex.
- Article
- Review
- Transgenic Techniques for Investigating Cell Biology During Development.Advances in experimental medicine and biology · 2018Review
- The Comparative Organismal Approach in Evolutionary Developmental Biology: Insights from Ascidians and Cavefish.Current topics in developmental biology · 2016Review
- Myogenesis in the sea urchin embryo: the molecular fingerprint of the myoblast precursors.EvoDevo · 2013Article
- Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans.EvoDevo · 2010Article
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1 author at 1 institution in 1 country.
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Abstract
In anural (tailless) ascidian species, functional embryonic muscle is not formed. In urodele (tailed) ascidians, macho-1 functions as a maternally supplied factor for embryonic muscle formation. The failure of embryonic muscle development in anural ascidians may be due to the suppression of macho-1 expression. In this paper, however, we report the expression of macho-1 in embryos of an anural ascidian, Molgula tectiformis. Although M. tectiformis has lost the developmental potential to form functional embryonic muscle, macho-1 was expressed in a very similar manner as in urodele ascidians. This result, together with those of previous studies, strongly suggests that in M. tectiformis the upstream genetic cascade responsible for muscle formation is intact, while the downstream cascade including the expression of muscle structural genes is severely affected.
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