ArticlePlant physiology2006
Light-regulated, tissue-specific, and cell differentiation-specific expression of the Arabidopsis Fe(III)-chelate reductase gene AtFRO6.
Article in Plant physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- The SVP-FRO6 Module Integrates the Control of Leaf Senescence and Flowering in Arabidopsis.Plant, cell & environment · 2026Article
- Iron deficiency changes regulatory mechanisms governing sieve element cell differentiation.Nature communications · 2025Article
- What Is Similar, What Is Different? Characterization of Mitoferrin-like Proteins fromInternational journal of molecular sciences · 2025Article
- The genomics and physiology of abiotic stressors associated with global elevational gradients in Arabidopsis thaliana.The New phytologist · 2024Article
- A combination of plasma membrane sterol biosynthesis and autophagy is required for shade-induced hypocotyl elongation.Nature communications · 2022Article
- Regulation of Iron Homeostasis and Use in Chloroplasts.International journal of molecular sciences · 2020Review
- The Adaptive Mechanism of Plants to Iron Deficiency via Iron Uptake, Transport, and Homeostasis.International journal of molecular sciences · 2019Review
- Elucidation and functional characterization of CsPSY and CsUGT promoters in Crocus sativus L.PloS one · 2018Article
- Dealing with iron metabolism in rice: from breeding for stress tolerance to biofortification.Genetics and molecular biology · 2017Article
- Utility and Limitations of Using Gene Expression Data to Identify Functional Associations.PLoS computational biology · 2016Article
- GENERAL CONTROL NONREPRESSED PROTEIN5-Mediated Histone Acetylation of FERRIC REDUCTASE DEFECTIVE3 Contributes to Iron Homeostasis in Arabidopsis.Plant physiology · 2015Article
- Local and systemic signaling of iron status and its interactions with homeostasis of other essential elements.Frontiers in plant science · 2015Review
- Auxin overproduction in shoots cannot rescue auxin deficiencies in Arabidopsis roots.Plant & cell physiology · 2014Article
- The diverse roles of FRO family metalloreductases in iron and copper homeostasis.Frontiers in plant science · 2014Review
- Evaluation of constitutive iron reductase (AtFRO2) expression on mineral accumulation and distribution in soybean (Glycine max. L).Frontiers in plant science · 2014Article
- Article
- Heterologous functional analysis of the Malus xiaojinensis MxIRT1 gene and the His-box motif by expression in yeast.Molecular biology reports · 2013Article
- Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs.PloS one · 2013Article
- Overexpression of AtFRO6 in transgenic tobacco enhances ferric chelate reductase activity in leaves and increases tolerance to iron-deficiency chlorosis.Molecular biology reports · 2011Article
- LEAFY COTYLEDON1 is a key regulator of fatty acid biosynthesis in Arabidopsis.Plant physiology · 2008Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron is an essential element for almost all living organisms, actively involved in a variety of cellular activities. To acquire iron from soil, strategy I plants such as Arabidopsis (Arabidopsis thaliana) must first reduce ferric to ferrous iron by Fe(III)-chelate reductases (FROs). FRO genes display distinctive expression patterns in several plant species. However, regulation of FRO genes is not well understood. Here, we report a systematic characterization of the AtFRO6 expression during plant growth and development. AtFRO6, encoding a putative FRO, is specifically expressed in green-aerial tissues in a light-dependent manner. Analysis of mutant promoter-beta-glucuronidase reporter genes in transgenic Arabidopsis plants revealed the presence of multiple light-responsive elements in the AtFRO6 promoter. These light-responsive elements may act synergistically to confer light responsiveness to the AtFRO6 promoter. Moreover, no AtFRO6 expression was detected in dedifferentiated green calli of the korrigan1-2 (kor1-2) mutant or undifferentiated calli derived from wild-type explants. Conversely, AtFRO6 is expressed in redifferentiated kor1-2 shoot-like structures and differentiating calli of wild-type explants. In addition, AtFRO7, but not AtFRO5 and AtFRO8, also shows a reduced expression level in kor1-2 green calli. These results suggest that whereas photosynthesis is necessary but not sufficient, both light and cell differentiation are necessary for AtFRO6 expression. We propose that AtFRO6 expression is light regulated in a tissue- or cell differentiation-specific manner to facilitate the acquisition of iron in response to distinctive developmental cues.
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