ReviewThe British journal of ophthalmology2006
Mechanosensitivity and the eye: cells coping with the pressure.
Review in The British journal of ophthalmology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Selective retinal neuron loss and impaired neurovascular support underlie myopic retinopathy in RPE-specific Lrp2-deficient mice.Frontiers in cellular neuroscience · 2026Article
- Sustained Experimental Myopia Exacerbates the Effect of Eye Growth on Retinal Ganglion Cell Density and Function.International journal of molecular sciences · 2025Article
- Investigation of the surface mechanical properties of functionalized single-walled carbon nanotube (SWCNT) reinforced PDMS nanocomposites using nanoindentation analysis.RSC advances · 2024Article
- Aqueous Humor Circulation in the Era of Minimally Invasive Surgery for Glaucoma.Annals of biomedical engineering · 2024Article
- The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes.Investigative ophthalmology & visual science · 2023Article
- Beneficial and Detrimental Pressure-Related Effects on Inner Neurons in the Adult Porcine In Vitro Retina.Translational vision science & technology · 2023Article
- Biophysical properties of corneal cells reflect high myopia progression.Biophysical journal · 2021Article
- Roles of the ocular pressure, pressure-sensitive ion channel, and elasticity in pressure-induced retinal diseases.Neural regeneration research · 2021Article
- Transient Intraocular Pressure Fluctuations: Source, Magnitude, Frequency, and Associated Mechanical Energy.Investigative ophthalmology & visual science · 2019Article
- The expression and function of TRPV4 channels in primate retinal ganglion cells and bipolar cells.Cell death & disease · 2019Article
- Racioethnic differences in the biomechanical response of the lamina cribrosa.Acta biomaterialia · 2019Article
- Investigating the Effects of Mechanical Stimulation on Retinal Ganglion Cell Spontaneous Spiking Activity.Frontiers in neuroscience · 2019Article
- Gaze-Evoked Deformations in Optic Nerve Head Drusen: Repetitive Shearing as a Potential Factor in the Visual and Vascular Complications.Ophthalmology · 2018Article
- The role of integrins in glaucoma.Experimental eye research · 2017Review
- Optically transparent multi-suction electrode arrays.Frontiers in neuroscience · 2015Article
- Development of diagnostic and treatment strategies for glaucoma through understanding and modification of scleral and lamina cribrosa connective tissue.Cell and tissue research · 2013Review
- On the somatosensation of vision.Annals of neurosciences · 2012Review
- Glaucomatous cupping of the lamina cribrosa: a review of the evidence for active progressive remodeling as a mechanism.Experimental eye research · 2011Review
- An applet to estimate the IOP-induced stress and strain within the optic nerve head.Investigative ophthalmology & visual science · 2011Article
- Mechanotransduction gone awry.Nature reviews. Molecular cell biology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cells of the various organ systems in humans are subject to mechanical forces to which they must respond. Here the authors review what is known of the ways in which the cells of animals, ranging from the prokaryotic to humans, sense and transduce mechanical forces to respond to such stimuli. In what way this pertains to the eye, especially with respect to axial myopia and the pressure related disease of glaucoma, is then surveyed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.