ArticleJournal of neurology, neurosurgery, and psychiatry2006
Feasibility and cost efficiency of a diagnostic guideline for chronic polyneuropathy: a prospective implementation study.
Article in Journal of neurology, neurosurgery, and psychiatry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies.medRxiv : the preprint server for health sciences · 2025Article
- Toward a Useful and Cost-Effective Workup in Chronic Polyneuropathy: The EXPRESS Study Protocol.Neuroepidemiology · 2025Observational
- Knowledge gaps in diagnosing chronic polyneuropathy: Review of national guidelines.Journal of the peripheral nervous system : JPNS · 2024Review
- Pattern, causes and functional outcome of peripheral neuropathies in the Amazon region.PloS one · 2024Observational
- The epidemiology and risk factors of chronic polyneuropathy.European journal of epidemiology · 2016Review
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtensive investigations are often performed to reveal the cause of chronic polyneuropathy. It is not known whether a restrictive diagnostic guideline improves cost efficiency without loss of diagnostic reliability.
methodsIn a prospective multicentre study, a comparison was made between the workup in patients with chronic polyneuropathy before and after guideline implementation.
resultsThree hundred and ten patients were included: 173 before and 137 after guideline implementation. In all patients, the diagnosis would remain the same if the workup was limited to the investigations in the guideline. After guideline implementation, the time to reach a diagnosis decreased by two weeks. There was a reduction of 33% in the number and costs of routine laboratory investigations/patient, and a reduction of 27% in the total number of laboratory tests/patient, despite low guideline adherence.
conclusionThe implementation of a diagnostic guideline for chronic polyneuropathy can reduce diagnostic delay and the number and costs of investigations for each patient without loss of diagnostic reliability. Continuous evaluation strategies after guideline implementation may improve guideline adherence and cost efficiency.
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