ArticleJournal of neurology, neurosurgery, and psychiatry2006
Additional causes for distal sensory polyneuropathy in diabetic patients.
Article in Journal of neurology, neurosurgery, and psychiatry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 77 citations in OpenAlex.
- Prevalence and associated factors of peripheral neuropathy in individuals with type 2 diabetes mellitus: a cross-sectional study in Khartoum State.BMC endocrine disorders · 2025Article
- Knowledge gaps in diagnosing chronic polyneuropathy: Review of national guidelines.Journal of the peripheral nervous system : JPNS · 2024Review
- Expert opinion on screening, diagnosis and management of diabetic peripheral neuropathy: a multidisciplinary approach.Frontiers in endocrinology · 2024Review
- Association of reproductive factors and exogenous hormone use with distal sensory polyneuropathy among postmenopausal women in the United States: results from 1999 to 2004 NHANES.Scientific reports · 2023Article
- Review
- Diagnosis and management of patients with polyneuropathy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Review
- Association Between Breastfeeding and Reduced Distal Sensory Polyneuropathy in Postmenopausal Women Aged 40-70 Years: Analysis of Data from the 1999-2004 National Health and Nutrition Examination Survey.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2023Article
- Comparison of diabetic and idiopathic sensory polyneuropathies with respect to nerve fibre affection and risk factors.BMJ neurology open · 2022Article
- The Role of Biofactors in Diabetic Microvascular Complications.Current diabetes reviews · 2022Article
- Observational
- [Diabetic neuropathy: do not only consider distal symmetrical neuropathy].Der Nervenarzt · 2015Review
- Not all neuropathy in diabetes is of diabetic etiology: differential diagnosis of diabetic neuropathy.Current diabetes reports · 2009Review
- High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.Diabetologia · 2007Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the frequency of additional causes of distal sensory polyneuropathy (DSP) in patients with diabetes mellitus (DM).
methodsRetrospective review of patients with DM and DSP during a 5 year period. A quantitative sensory score (QSS) was determined at the initial evaluation and extensive laboratory and EMG studies were performed. Patients with one or more potential causes for DSP were compared to those with DM alone.
resultsFifty five patients (53%) had potential additional causes for DSP. These included: neurotoxic medications (seven), alcohol abuse (six), and B12 deficiency and renal disease (four each). The most common laboratory abnormalities were: abnormally low levels of vitamin B6 (11) or B1 (10), monoclonal gammopathy (eight), and hypertriglyceridaemia (eight). Twenty six (25%) subjects had more than one additional cause. Nine (9%) had three or more demyelinating features on EMG. There was a trend toward a lower QSS score (p = 0.05) and reduced mean amplitude of the sensory potentials in those with additional causes. Those with additional causes more often had upper limb sensory symptoms (p = 0.001) and sensory findings (p = 0.003).
conclusionThere was a high frequency of additional sources of DSP in patients with DM. These patients more often had sensory symptoms and findings in the hands. Tests that may be useful in the evaluation of DSP in diabetic patients include measures of vitamins B1, B6, B12, serum triglycerides, and immunofixation.
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