Evidence map›Paper›PMID 16484239›Full record

SynthesisBMJ (Clinical research ed.)2006

Factors predisposing women to chronic pelvic pain: systematic review.

Pallavi Latthe, Luciano Mignini, Richard Gray, Robert Hills, Khalid Khan

2 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 140 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 12 pooled it
29.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04091789 phase2unknown statusnot on this mapstarted 2019, after this paper: background citation

A Controlled-Dose Study Using Cannabinoid Combinations in a Rapidly Dissolvable Sublingual Tablet for the Treatment of Dysmenorrhea and Associated Pain Symptoms

TypeinterventionalSponsorPure GreenRan2019 to 2020Enrolled30ConditionsDysmenorrhea, Headache, Migraine, Fatigue, NauseaArmsPure Femme Tablets
NCT05622955 nacompletednot on this mapstarted 2023, after this paper: background citation

A Novel Approach to Endometriosis Treatment: Piloting an Interdisciplinary Group Care Model

TypeinterventionalSponsorWashington University School of MedicineRan2023 to 2025Enrolled35ConditionsEndometriosis, Pelvic PainArmsPeer Empowered Endometriosis Pain Support (PEEPS)
3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 12 syntheses or guidelines pooled it, 572 citations in OpenAlex.

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  7. WITHDRAWN: Exercise for dysmenorrhoea.The Cochrane database of systematic reviews · 2017
    Pooled it
  8. Dysmenorrhoea.BMJ clinical evidence · 2014
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  10. Dysmenorrhoea.BMJ clinical evidence · 2011
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80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pallavi LattheAcademic Department of Obstetrics and Gynaecology, University of Birmingham, Birmingham B15 2TG. pallavi@doctors.org.uk
Luciano Mignini
Richard Gray
Robert Hills
Khalid Khan
University of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate factors predisposing women to chronic and recurrent pelvic pain. DESIGN, DATA SOURCES, AND

methodsSystematic review of relevant studies without language restrictions identified through Medline, Embase, PsycINFO, Cochrane Library. SCISEARCH, conference papers, and bibliographies of retrieved primary and review articles. Two reviewers independently extracted data on study characteristics, quality, and results. Exposure to risk factors was compared between women with and without pelvic pain. Results were pooled within subgroups defined by type of pain and risk factors.

resultsThere were 122 studies (in 111 articles) of which 63 (in 64,286 women) evaluated 54 risk factors for dysmenorrhoea, 19 (in 18,601 women) evaluated 14 risk factors for dyspareunia, and 40 (in 12,040 women) evaluated 48 factors for non-cyclical pelvic pain. Age < 30 years, low body mass index, smoking, earlier menarche (< 12 years), longer cycles, heavy menstrual flow, nulliparity, premenstrual syndrome, sterilisation, clinically suspected pelvic inflammatory disease, sexual abuse, and psychological symptoms were associated with dysmenorrhoea. Younger age at first childbirth, exercise, and oral contraceptives were negatively associated with dysmenorrhoea. Menopause, pelvic inflammatory disease, sexual abuse, anxiety, and depression were associated with dyspareunia. Drug or alcohol abuse, miscarriage, heavy menstrual flow, pelvic inflammatory disease, previous caesarean section, pelvic pathology, abuse, and psychological comorbidity were associated with an increased risk of non-cyclical pelvic pain.

conclusionSeveral gynaecological and psychosocial factors are strongly associated with chronic pelvic pain. Randomised controlled trials of interventions targeting these potentially modifiable factors are needed to assess their clinical relevance in chronic pelvic pain.

Indexed as

Chronic DiseaseDysmenorrheaDyspareuniaFemaleHumansPelvic PainRegression AnalysisRisk Factors

Identifiers

PMID16484239
PMCPMC1420707
OpenAlexW1964599001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.