Evidence map›Paper›PMID 16480510›Full record

ArticleBMC bioinformatics2006

BIOZON: a system for unification, management and analysis of heterogeneous biological data.

Aaron Birkland, Golan Yona

Abstract read
In one paragraph

Article in BMC bioinformatics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Integrated data-driven biotechnology research environments.Database : the journal of biological databases and curation · 2025
    Review
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  9. JBioWH: an open-source Java framework for bioinformatics data integration.Database : the journal of biological databases and curation · 2013
    Article
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  18. An advanced web query interface for biological databases.Database : the journal of biological databases and curation · 2010
    Article
  19. Semantic integration of data on transcriptional regulation.Bioinformatics (Oxford, England) · 2010
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aaron BirklandDepartment of Computer Science, Cornell University, Ithaca, NY, USA. birkland@cs.cornell.edu
Golan Yona

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntegration of heterogeneous data types is a challenging problem, especially in biology, where the number of databases and data types increase rapidly. Amongst the problems that one has to face are integrity, consistency, redundancy, connectivity, expressiveness and updatability. DESCRIPTION: Here we present a system (Biozon) that addresses these problems, and offers biologists a new knowledge resource to navigate through and explore. Biozon unifies multiple biological databases consisting of a variety of data types (such as DNA sequences, proteins, interactions and cellular pathways). It is fundamentally different from previous efforts as it uses a single extensive and tightly connected graph schema wrapped with hierarchical ontology of documents and relations. Beyond warehousing existing data, Biozon computes and stores novel derived data, such as similarity relationships and functional predictions. The integration of similarity data allows propagation of knowledge through inference and fuzzy searches. Sophisticated methods of query that span multiple data types were implemented and first-of-a-kind biological ranking systems were explored and integrated.

conclusionThe Biozon system is an extensive knowledge resource of heterogeneous biological data. Currently, it holds more than 100 million biological documents and 6.5 billion relations between them. The database is accessible through an advanced web interface that supports complex queries, "fuzzy" searches, data materialization and more, online at http://biozon.org.

Indexed as

AnimalsBiologyComputational BiologyComputer GraphicsDatabase Management SystemsDatabases, FactualDatabases, GeneticDatabases, ProteinHumansInformation Storage and RetrievalInternetModels, StatisticalProgramming LanguagesResearchSequence Analysis, DNASoftware

Identifiers

PMID16480510
PMCPMC1449871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.