Evidence map›Paper›PMID 16479314›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2006

Diagnostic value of C-reactive protein in discriminating fungal from nonfungal pulmonary infiltrates in patients with hematologic malignancies.

Massimo Offidani, Laura Corvatta, Lara Malerba, Maria-Novella Piersantelli, Esther Manso, Pietro Leoni

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Biomarkers: a definite plus in pneumonia.Mediators of inflammation · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Massimo OffidaniClinica di Ematologia, Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy, m.offidani@ao-umbertoprimo.marche.it.
Laura Corvatta
Lara Malerba
Maria-Novella Piersantelli
Esther Manso
Pietro Leoni
Marche Polytechnic University · ITSan Salvatore Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to assess the utility of C-reactive protein (CRP) on differential diagnosis of pulmonary infiltrates occurring in 143 febrile patients with hematologic malignancies. Serum CRP level, measured on the first day of pneumonia, was significantly higher in patients with fungal lung infiltrates than in those with nonfungal pneumonia (22.3 mg/dl vs 7.3 mg/dl; p<0.0001). Predictive factors for fungal pneumonia were CRP level higher than 10 mg/dl, neutropenia longer than 10 days, and active underlying disease.

Indexed as

AdultAgedAnalysis of VarianceBiomarkersC-Reactive ProteinDiagnosis, DifferentialFemaleHematologic NeoplasmsHumansLung Diseases, FungalMaleMiddle AgedPneumoniaPneumonia, BacterialPredictive Value of TestsRetrospective StudiesBiomarkersC-Reactive Protein

Identifiers

PMID16479314
OpenAlexW2025146127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.