ReviewThe Journal of cell biology2006
Nuclear actin: to polymerize or not to polymerize.
Review in The Journal of cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 46 citations in OpenAlex.
- DNase I as a probe for unpolymerized actin: revisiting a classic tool for nuclear actin research.Pflugers Archiv : European journal of physiology · 2026Review
- The functional importance of lamins, actin, myosin, spectrin and the LINC complex in DNA repair.Experimental biology and medicine (Maywood, N.J.) · 2019Review
- Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genes.Cell death and differentiation · 2016Article
- Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.Genes & development · 2014Article
- Cell-type specificity of β-actin expression and its clinicopathological correlation in gastric adenocarcinoma.World journal of gastroenterology · 2014Article
- Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.Nature cell biology · 2014Article
- A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells.Nature cell biology · 2013Article
- On the role of DNA biomechanics in the regulation of gene expression.Journal of the Royal Society, Interface · 2011Review
- Post-translational control of Myc function during differentiation.Cell cycle (Georgetown, Tex.) · 2011Article
- STK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cells.PloS one · 2011Article
- Depletion of nuclear actin is a key mediator of quiescence in epithelial cells.Journal of cell science · 2011Article
- Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks.The Journal of experimental medicine · 2010Article
- Identification of FBXO25-interacting proteins using an integrated proteomics approach.Proteomics · 2010Article
- Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores.PLoS genetics · 2010Article
- Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.PloS one · 2010Article
- Article
- Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression.The FEBS journal · 2009Review
- Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Nuclear actin depolymerization in transcriptionally active avian and amphibian oocytes leads to collapse of intranuclear structures.Nucleus (Austin, Tex.)Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The form and function of actin in the nucleus have been enigmatic for over 30 years. Recently actin has been assigned numerous functional roles in the nucleus, but its form remains a mystery. The intricate relationship between actin form and function in the cytoplasm implies that understanding the structural properties of nuclear actin is elementary to fully understanding its function. In this issue, McDonald et al. (p. 541) use fluorescence recovery after photobleaching (FRAP) to tackle the question of whether nuclear actin exists as monomers or polymers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.