Evidence map›Paper›PMID 16476189›Full record

ReviewCurrent allergy and asthma reports2006

Cardiac anaphylaxis: pathophysiology and therapeutic perspectives.

Daniele Bani, Silvia Nistri, Pier Francesco Mannaioni, Emanuela Masini

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Function and Role of Histamine HPharmaceuticals (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Kounis syndrome, two case reports from Kragujevac, Serbia.American journal of cardiovascular disease · 2014
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniele BaniDepartment of Anatomy, Histology & Forensic Medicine, Section of Histology, University of Florence, Viale G. Pieraccini, 6, I-50139 Florence, Italy. daniele.bani@unifi.it
Silvia Nistri
Pier Francesco Mannaioni
Emanuela Masini
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac anaphylaxis refers to the functional and metabolic changes in the heart caused by the anaphylactic release of histamine and vasoactive products of arachidonic acid cascade by mast cells and basophils. As in most type I hypersensitivity-based diseases, histamine plays a key role in the pathophysiology of cardiac anaphylaxis. In the heart, mast cell activation and histamine release are controlled by multiple endogenous mechanisms, including adrenergic neural control, histamine-dependent negative feedback operated through H2 receptors, and the endogenous generation of nitric oxide (NO) and carbon monoxide (CO). All these mechanisms can be targeted by substances that have revealed a clear-cut effect in blunting cardiac anaphylaxis in experimental animal models, and could be developed as potential, novel anti-anaphylactic drugs. In this article, we discuss new findings and significant trends related to this topic.

Indexed as

Amine Oxidase (Copper-Containing)AnaphylaxisAnimalsCarbon MonoxideHeart DiseasesHistamineHistamine AntagonistsHistamine ReleaseHumansMast CellsNitric OxideRelaxinAmine Oxidase (Copper-Containing)Carbon MonoxideHistamineHistamine AntagonistsNitric OxideRelaxin

Identifiers

PMID16476189
OpenAlexW2068902832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.