ArticleFolia microbiologica2005
Intramucosal bacteria in colon cancer and their elimination by probiotic strain Enterococcus faecium M-74 with organic selenium.
Article in Folia microbiologica, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 40 citations in OpenAlex.
- Oral application of Enterococcus faecium strain EE3 in healthy dogs.Folia microbiologica · 2006Trial
- Selenium and probiotics co-supplementation: A scoping review of clinical evidence.Inflammopharmacology · 2026Article
- Mineral-Enriched Postbiotics: A New Perspective for Microbial Therapy to Prevent and Treat Gut Dysbiosis.Biomedicines · 2022Review
- Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases.Frontiers in nutrition · 2021Review
- Intestinal microbiota: a novel perspective in colorectal cancer biotherapeutics.OncoTargets and therapy · 2018Review
- Role of Probiotics in health improvement, infection control and disease treatment and management.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2015Review
- Inhibitory potential of lactobacilli against Escherichia coli internalization by HT 29 cells.Folia microbiologica · 2012Article
- Probiotic potential of enterococci isolated from canine feed.Folia microbiologica · 2008Article
- Adaptation of adhesion test using Caco-2 cells for anaerobic bacterium Pseudobutyrivibrio xylanivorans, a probiotic candidate.Folia microbiologica · 2007Article
- Properties of the strains Enterococcus haemoperoxidus and E. moraviensis, new species among enterococci.Folia microbiologica · 2007Article
- Antimicrobial susceptibility of Enterococcus species isolated from Slovak Bryndza cheese.Folia microbiologica · 2007Article
- Effect of lactobacilli on E. coli adhesion to Caco-2 cells in vitro.Folia microbiologica · 2006Article
- Probiotics manipulate host cytokine response and induce antimicrobial peptides.Folia microbiologica · 2006Review
- Oral administration of probiotic bacteria (E. coli Nissle, E. coli O83, Lactobacillus casei) influences the severity of dextran sodium sulfate-induced colitis in BALB/c mice.Folia microbiologica · 2006Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intraepithelial bacteria were isolated by the gentamicin protection assay (GPA) from biopsy samples obtained at colonoscopy (colon cancer, n = 10 patients; colonic adenoma, n = 20; control group, n = 20; cancer patients without gastrointestinal tract GIT malignancy, n = 10). After a three-month administration of E. faecium M-74 to patients with positive GPA biopsies, 172 biopsy specimens from 60 patients were examined with the GPA. The number of biopsies with intracellular bacteria was significantly higher in adenoma and carcinoma group than in control group (26 vs. 10%; p = 0.004); in cancer patients without GIT malignancy the difference was nonsignificant. E. faecium M-74 was also administered to 5 patients with colonic adenoma; according to a control colonoscopy the number of biopsies with intracellular bacteria was significantly lower after probiotic administration (48 vs. 16%; p = 0.03). A striking prevalence of intraepithelial bacteria was also showed in patients with large bowel adenoma and carcinoma. The administration of probiotic strain M-74 can thus be considered to be an effective and promising method for elimination of pathogenic bacteria in the case of inflammatory bowel disease and colon cancer.
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Registered trials
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