Evidence map›Paper›PMID 16475040›Full record

ReviewJournal of thrombosis and thrombolysis2006

The post-thrombotic syndrome: the forgotten morbidity of deep venous thrombosis.

Susan R Kahn

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of thrombosis and thrombolysis, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00790335 (Acute Venous Thrombosis), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00790335 phase3completednot on this mapstarted 2009, after this paper: background citation

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis--The ATTRACT Trial

TypeinterventionalSponsorWashington University School of MedicineRan2009 to 2017Enrolled692ConditionsDeep Vein Thrombosis, Venous Thrombosis, Postphlebitic Syndrome, Venous ThromboembolismArmsRecombinant tissue plasminogen activator (rt-PA)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Revascularization of acute inferior vena cava thrombosis and atresia in an adolescent.Journal of vascular surgery cases and innovative techniques · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Heparin: 100 years of pleiotropic effects.Journal of thrombosis and thrombolysis · 2016
    Review
  15. Review
  16. Article
  17. Venous Ulcers.The journal of the American College of Clinical Wound Specialists · 2012
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Susan R KahnDepartment of Medicine, McGill University, and Center for Clinical Epidemiology & Community Studies, Sir Mortimer B. Davis Jewish General Hospital, 3755 Cote Sainte-Catherine, Room A-127, Montreal, Quebec, Canada H3T 1E2. susan.kahn@mcgill.ca
Jewish General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The postthrombotic syndrome (PTS) is the most common complication of deep venous thrombosis (DVT) yet has received little attention from clinicians and researchers. Clinically, PTS is characterized by chronic pain, swelling, heaviness and other signs in the affected limb. In severe cases, venous ulcers may develop. PTS is burdensome and costly to patients and society because of its high prevalence, severity and chronicity. Preventing DVT with the use of effective thromboprophylaxis in high-risk patients and settings and minimizing the risk of ipsilateral DVT recurrence are likely to reduce the frequency of PTS. Compression stockings worn daily after DVT appear to reduce the incidence and severity of PTS but questions regarding their use and effectiveness remain. Future research should focus on identifying patients at high risk for PTS, assessing the role of thrombolysis in preventing PTS and evaluating the optimal use of compression stockings in preventing and treating PTS. In addition, new therapies to treat PTS should be sought and evaluated.

Indexed as

HumansPrevalenceRecurrenceRisk FactorsSyndromeVenous Thrombosis

Identifiers

PMID16475040
OpenAlexW1993112954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.