Evidence map›Paper›PMID 16474077›Full record

ArticleThe American journal of tropical medicine and hygiene2006

Morbidity and mortality profile of human immunodeficiency virus-infected patients with and without hepatitis C co-infection.

Angel M Mayor, Maria A Gomez, Diana M Fernandez, Eddy Rios-Olivares, James C Thomas, Robert F Hunter

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Meta-analysis: increased mortality associated with hepatitis C in HIV-infected persons is unrelated to HIV disease progression.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2009
    Pooled it
  2. Observational
  3. Comparison of Hepatitis C Virus RNA and antibody detection in dried blood spots and plasma specimens.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2014
    Article
  4. Article
  5. The current seroprevalence of hepatitis C virus in a tertiary care centre in vellore, Tamil Nadu.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2012
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Angel M MayorRetrovirus Research Center, and Department of Microbiology, Universidad Central del Caribe, School of Medicine, Bayamón, Puerto Rico. amayorb@hotmail.com
Maria A Gomez
Diana M Fernandez
Eddy Rios-Olivares
James C Thomas
Robert F Hunter
Central University of the Caribbean · PR

Funding

UNIVERSITY MEDICAL RESEARCH CENTERG12RR003035 · NCRR · UNIVERSIDAD CENTRAL DEL CARIBE · PI ROJAS, LEGIER V · 1986 to 2011
$26.7M
TRANSLATION AND CULTURAL ADAPTATION OF THE PRIMARY CARE ASSESSMENT TOOLU54RR019507 · NCRR · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ZORRILLA, CARMEN D · 2003 to 2009
$14.2M
UNIVERSIDAD CENTRAL DEL CARIBE BIOMEDICAL RESEARCH CENTERSG12MD007583 · NIMHD · UNIVERSIDAD CENTRAL DEL CARIBE · PI RODRIGUEZ, JOSE GINEL · 2012 to 2016
$8.4M
NCRR NIH HHS 1U54RR01950701NCRR NIH HHS G12 RR003035NCRR NIH HHS G12RR03035NCRR NIH HHS U54 RR019507NIMHD NIH HHS G12 MD007583PHS HHS U62/CCU206209
6 · The paper itself

Abstract

Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) co-infection is an important and frequent scenario, predominantly in injecting drug users (IDUs). The present study evaluated morbidity and mortality variation in HIV-infected patients with and without HCV co-infection. Co-infection prevalence was determined in 356 HIV-infected persons. Their clinical manifestations, laboratory findings, risk factors, HIV therapies, and mortality rates were evaluated. The prevalence of HCV was 54% in the overall group and 81% in IDUs, with a predominance of HCV genotype 1. Mortality rates were similar in patients with and without co-infection; however, co-infected patients had significantly higher liver damage as a cause of mortality when compared with those who were not co-infected. The high prevalence of HCV and an emerging mortality from liver diseases showed the significance of this co-infection in the HIV epidemic. Primary and secondary prevention are necessary to reduce the expanding impact of HCV infection in HIV patients.

Indexed as

Substance Abuse, IntravenousAdultAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountComorbidityFemaleHepacivirusHepatitis CHIVHIV InfectionsHumansMalePrevalencePuerto RicoRisk FactorsSurveys and Questionnaires

Identifiers

PMID16474077
PMCPMC3938120
OpenAlexW2101393072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.