ArticleThe journal of physical chemistry. B2006
A model for DNA detection by metal-enhanced fluorescence from immobilized silver nanoparticles on solid substrate.
Article in The journal of physical chemistry. B, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Bimetallic Nanoshells for Metal - Enhanced Fluorescence with Broad Band Fluorophores.The journal of physical chemistry. C, Nanomaterials and interfaces · 2012Article
- Single molecule photophysics near metallic nanostructures.Proceedings of SPIE--the International Society for Optical Engineering · 2008Article
- Metal-Enhanced Fluorescence of Phycobiliproteins from Heterogeneous Plasmonic Nanostructures.The journal of physical chemistry. C, Nanomaterials and interfaces · 2007Article
- Single-Molecule Studies of Enhanced Fluorescence on Silver Island Films.Plasmonics (Norwell, Mass.) · 2007Article
- Distance-dependent emission from dye-labeled oligonucleotides on striped Au/Ag nanowires: effect of secondary structure and hybridization efficiency.Journal of the American Chemical Society · 2006Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
N-(2-Mercaptopropionyl)glycine (tiopronin)-coated silver nanoparticles (average diameter of metal core=5 nm) were prepared by a modified Brust method. Tiopronin ligands were partially displaced by thiolate single-stranded oligonucleotides via ligand exchange. These particles were immobilized onto a solid substrate through hybridization with target oligonucleotides in a layer-by-layer approach. The dye-labeled complementary oligonucleotides were bound to the particle layers through hybridization. Fluorescence intensity was enhanced with a simultaneous increase of plasmon absorbance from accumulated particles. A steady state was shown at the 10th particle layer and then the fluorescence enhancement showed a plateau. This result reveals that increasing the particle layer contributes to fluorescence enhancement. This novel method was used to detect DNA hybridization through both absorbance and emission spectral changes.
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Registered trials
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