Evidence map›Paper›PMID 16469274›Full record

ArticleCurrent neurology and neuroscience reports2006

Current therapies for neuromuscular manifestations of paraneoplastic syndromes.

Myrna R Rosenfeld, Josep Dalmau

Abstract read
PubMed Publisher
In one paragraph

Article in Current neurology and neuroscience reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Progress in the management of paraneoplastic neurological disorders.Therapeutic advances in neurological disorders · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Myrna R RosenfeldDepartment of Neurology, Section of Neuro-Oncology, 3 West Gates, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Josep Dalmau
University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neuromuscular manifestations of paraneoplastic disorders result in diverse syndromes that may also occur in patients without cancer. In general, treatment of these disorders is the same whether or not there is an underlying malignancy. However, when the disorder is believed to be paraneoplastic, the main concern should be prompt detection and treatment of the tumor, as this has been shown to offer the best chance for neurologic stabilization or improvement. The paraneoplastic neuromuscular disorders can be divided into two main categories: those that are directly mediated by antibodies and those that are believed to result from other immune-mediated mechanisms, including cytotoxic T-cell responses with or without association with specific antibodies. For disorders in which the antibodies are pathogenic, therapy is aimed at removing the antibodies. For the other disorders, adjuvant therapies are for the most part empiric and include a variety of immunosuppressant and immunomodulatory agents.

Indexed as

Neuromuscular DiseasesParaneoplastic Syndromes, Nervous SystemAdrenal Cortex HormonesAntibodiesAutoantibodiesHumansImmunoglobulins, IntravenousImmunologic FactorsImmunosuppressive AgentsPlasma ExchangeAdrenal Cortex HormonesAntibodiesAutoantibodiesImmunoglobulins, IntravenousImmunologic FactorsImmunosuppressive Agents

Identifiers

PMID16469274
OpenAlexW2047799989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.