SynthesisBMJ (Clinical research ed.)2006
Factors influencing death at home in terminally ill patients with cancer: systematic review.
Synthesis in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 312 papers, 20 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
312 citing papers in PubMed, 20 syntheses or guidelines pooled it.
- Factors associated with psychological distress among end-of-life care volunteers: a systematic review of quantitative and qualitative evidence.BMC palliative care · 2026Pooled it
- Unequal ends: A systematic review comparing place of death in rural, coastal and urban areas for older people with dementia to cancer.Palliative medicine · 2026Pooled it
- Place of death in Parkinson's disease: A systematic review and meta-analysis of associated factors.Journal of Parkinson's disease · 2026Pooled it
- Place of Death of People With Chronic Conditions in Latin America: A Systematic Review.Public health reviews · 2026Pooled it
- Geographic variations in place of death and palliative care utilisation in the last three months of life in high-income countries: a systematic review.BMC palliative care · 2025Pooled it
- Equitable inclusion of patients with cancer on the palliative care register: a systematic review in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Pooled it
- Fear of Cancer Recurrence Prevalence and Its Associated Factors Among Family Caregivers of Women With Breast Cancer: A Systematic Review and Meta-Analysis.Journal of clinical nursing · 2025Pooled it
- Factors Influencing the Quality of Life (QOL) of Advanced Cancer Patients in Home-based Palliative Care (HBPC): A Systematic Review.Asian Pacific journal of cancer prevention : APJCP · 2024Pooled it
- Home-based supportive care in advanced cancer: systematic review.BMJ supportive & palliative care · 2024Pooled it
- Factors associated with hospitalisations of patients with chronic heart failure approaching the end of life: A systematic review.Palliative medicine · 2022Pooled it
- Preferred Place of Death in Adult Cancer Patients: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2021Pooled it
- Socioeconomic position and use of healthcare in the last year of life: A systematic review and meta-analysis.PLoS medicine · 2019Pooled it
- Factors associated with older people's emergency department attendance towards the end of life: a systematic review.European journal of public health · 2019Pooled it
- The facilitators and challenges of dying at home with dementia: A narrative synthesis.Palliative medicine · 2018Pooled it
- Influences on Care Preferences of Older People with Advanced Illness: A Systematic Review and Thematic Synthesis.Journal of the American Geriatrics Society · 2018Pooled it
- Older Adults' Social Relationships and Health Care Utilization: A Systematic Review.American journal of public health · 2018Pooled it
- The preferences and perspectives of family caregivers towards place of care for their relatives at the end-of-life. A systematic review and thematic synthesis of the qualitative evidence.BMJ supportive & palliative care · 2016Pooled it
- How can we help family carers manage pain medicines for patients with advanced cancer? A systematic review of intervention studies.BMJ supportive & palliative care · 2016Pooled it
- Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review.Palliative medicine · 2016Pooled it
- The determinants of home and nursing home death: a systematic review and meta-analysis.BMC palliative care · 2016Pooled it
252 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the relative influence of different factors on place of death in patients with cancer. DATA SOURCES: Four electronic databases-Medline (1966-2004), PsycINFO (1972-2004), CINAHL (1982-2004), and ASSIA (1987-2004); previous contacts with key experts; hand search of six relevant journals. REVIEW
methodsWe generated a conceptual model, against which studies were analysed. Included studies had original data on risk factors for place of death among patients, > 80% of whom had cancer. Strength of evidence was assigned according to the quantity and quality of studies and consistency of findings. Odds ratios for home death were plotted for factors with high strength evidence.
results58 studies were included, with over 1.5 million patients from 13 countries. There was high strength evidence for the effect of 17 factors on place of death, of which six were strongly associated with home death: patients' low functional status (odds ratios range 2.29-11.1), their preferences (2.19-8.38), home care (1.37-5.1) and its intensity (1.06-8.65), living with relatives (1.78-7.85), and extended family support (2.28-5.47). The risk factors covered all groups of the model: related to illness, the individual, and the environment (healthcare input and social support), the latter found to be the most important.
conclusionsThe ne of factors that influence where patients with cancer die is complicated. Future policies and clinical practice should focus on ways of empowering families and public education, as well as intensifying home care, risk assessment, and training practitioners in end of life care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.