Evidence map›Paper›PMID 16464325›Full record

Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2006

Gut-directed hypnotherapy for irritable bowel syndrome: piloting a primary care-based randomised controlled trial.

Lesley Roberts, Sue Wilson, Sukhdev Singh, Andrea Roalfe, Sheila Greenfield

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC
In one paragraph

Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 7 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Irritable bowel syndrome.BMJ clinical evidence · 2012
    Pooled it
  4. Irritable bowel syndrome.BMJ clinical evidence · 2010
    Pooled it
  5. Pooled it
  6. Guideline
  7. Hypnotherapy for treatment of irritable bowel syndrome.The Cochrane database of systematic reviews · 2007
    Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Review
  12. Review
  13. Effectiveness of Non-Pharmacological Interventions for Irritable Bowel Syndrome: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Intestinal microbiota and immune function in the pathogenesis of irritable bowel syndrome.American journal of physiology. Gastrointestinal and liver physiology · 2013
    Review
  19. Neurophysiology of pain and hypnosis for chronic pain.Translational behavioral medicine · 2012
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lesley RobertsDepartment of Primary Care and General Practice, Division of Primary Care, Public and Occupational Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. robertslz@adf.bham.ac.uk
Sue Wilson
Sukhdev Singh
Andrea Roalfe
Sheila Greenfield
University of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn western populations irritable bowel syndrome (IBS) affects between 10% and 30% of the population and has a significant effect on quality of life. It generates a substantial workload in both primary and secondary care and has significant cost implications. Gut-directed hypnotherapy has been demonstrated to alleviate symptoms and improve quality of life but has not been assessed outside of secondary and tertiary referral centres.

aimTo assess the effectiveness of gut-directed hypnotherapy as a complementary therapy in the management of IBS. DESIGN OF STUDY: Randomised controlled trial.

settingPrimary care patients aged 18-65 years inclusive, with a diagnosis of IBS of greater than 6 weeks' duration and having failed conventional management, located in South Staffordshire and North Birmingham, UK.

methodIntervention patients received five sessions of hypnotherapy in addition to their usual management. Control patients received usual management alone. Data regarding symptoms and quality of life were collected at baseline and again 3, 6, and 12 months post-randomisation.

resultsBoth groups demonstrated a significant improvement in all symptom dimensions and quality of life over 12 months. At 3 months the intervention group had significantly greater improvements in pain, diarrhoea and overall symptom scores (P<0.05). No significant differences between groups in quality of life were identified. No differences were maintained over time. Intervention patients, however, were significantly less likely to require medication, and the majority described an improvement in their condition.

conclusionsGut-directed hypnotherapy benefits patients via symptom reduction and reduced medication usage, although the lack of significant difference between groups beyond 3 months prohibits its general introduction without additional evidence. A large trial incorporating robust economic analysis is, therefore, urgently recommended.

Indexed as

AdolescentAdultAgedFamily PracticeFemaleHumansHypnosisIrritable Bowel SyndromeMaleMiddle AgedPilot ProjectsQuality of LifeTreatment Outcome

Identifiers

PMID16464325
PMCPMC1828217
OpenAlexW1939585142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.