Evidence map›Paper›PMID 16464021›Full record

ReviewChemical reviews2006

Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair.

Mala Samaranayake, Janusz M Bujnicki, Michael Carpenter, Ashok S Bhagwat

Abstract readEvaluation StudyReview
In one paragraph

Review in Chemical reviews, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. SAR-CoV-2 infection, emerging new variants and the role of activation induced cytidine deaminase (AID) in lasting immunity.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  3. Review
  4. Article
  5. Article
  6. Transcription-associated mutagenesis.Annual review of genetics · 2014
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mala SamaranayakeDepartment of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.
Janusz M Bujnicki
Michael Carpenter
Ashok S Bhagwat

Funding

TRANSCRIPTION--INDUCED MUTATIONSR01GM057200 · NIGMS · WAYNE STATE UNIVERSITY · PI BHAGWAT, ASHOK S · 1998 to 2014
$2.6M
Discovering New Human DNA Repair Genes by BioinformaticsR33CA097899 · NCI · WAYNE STATE UNIVERSITY · PI BHAGWAT, ASHOK S · 2006 to 2007
$491k
Discovering New Human DNA Repair Genes by BioinformaticsR21CA097899 · NCI · WAYNE STATE UNIVERSITY · PI BHAGWAT, ASHOK S · 2003 to 2004
$260k
NCI NIH HHS CA97899NCI NIH HHS R21 CA097899NCI NIH HHS R33 CA097899NIGMS NIH HHS GM57200NIGMS NIH HHS R01 GM057200
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA RepairInsemination, Artificial, HeterologousModels, MolecularAmino Acid SequenceAnimalsAntibodiesBase Pair MismatchCytosineCytosine DeaminaseDeaminationDNADNA DamageHumansMolecular Sequence DataMutagenesisAntibodiesCytosineCytosine DeaminaseDNA

Identifiers

PMID16464021
PMCPMC4593474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.