GuidelineJournal of hepato-biliary-pancreatic surgery2006
JPN Guidelines for the management of acute pancreatitis: medical management of acute pancreatitis.
Guideline in Journal of hepato-biliary-pancreatic surgery, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis: UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG Evidence-Based Recommendations.United European gastroenterology journal · 2026Guideline
- Analgesia in the Initial Management of Acute Pancreatitis: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.World journal of surgery · 2022Pooled it
- Use of probiotics in the treatment of severe acute pancreatitis: a systematic review and meta-analysis of randomized controlled trials.Critical care (London, England) · 2014Pooled it
- Minimally invasive management of pancreatic abscess, pseudocyst, and necrosis: a systematic review of current guidelines.World journal of surgery · 2008Pooled it
- Rifaximin reduces gut-derived inflammation in severe acute pancreatitis: an experimental animal model and randomized controlled trial.Microbiology spectrum · 2025Trial
- No Benefit of Oral Diclofenac on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.Digestive diseases and sciences · 2016Trial
- Vancomycin is a risk factor for acute pancreatitis and increases the mortality rate in patients with severe pancreatitis.Frontiers in immunology · 2025Article
- Current trends in acute pancreatitis: Diagnostic and therapeutic challenges.World journal of gastroenterology · 2023Review
- Drug repurposing against coronavirus disease 2019 (COVID-19): A review.Journal of pharmaceutical analysis · 2021Review
- Review
- Association of asparaginase-associated pancreatitis and ULK2 gene polymorphism.International journal of clinical and experimental pathology · 2020Article
- Prophylactic antibiotics in acute pancreatitis: endless debate.Annals of the Royal College of Surgeons of England · 2017Article
- Effective and safe proton pump inhibitor therapy in acid-related diseases - A position paper addressing benefits and potential harms of acid suppression.BMC medicine · 2016Review
- Acute pancreatitis as a complication of childhood cancer treatment.Cancer medicine · 2016Review
- Perioperative management for pancreatoduodenectomy following severe acute pancreatitis in patients with periampullary cancer: our experience with six consecutive cases.Surgery today · 2015Article
- Study on acute recent stage pancreatitis.World journal of gastroenterology · 2014Review
- Treatment of severe acute pancreatitis and its complications.World journal of gastroenterology · 2014Review
- Early continuous veno-venous haemofiltration in the management of severe acute pancreatitis complicated with intra-abdominal hypertension: retrospective review of 10 years' experience.Annals of intensive care · 2012Article
- Management of severe acute pancreatitis.The Indian journal of surgery · 2012Article
- Utility of the new Japanese severity score and indications for special therapies in acute pancreatitis.Journal of gastroenterology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The basic principles of the initial management of acute pancreatitis are adequate monitoring of vital signs, fluid replacement, correction of any electrolyte imbalance, nutritional support, and the prevention of local and systemic complications. Patients with severe acute pancreatitis should be transferred to a medical facility where adequate monitoring and intensive medical care are available. Strict cardiovascular and respiratory monitoring is mandatory for maintaining the cardiopulmonary system in patients with severe acute pancreatitis. Maximum fluid replacement is needed to stabilize the cardiovascular system. Prophylactic antibiotic administration is recommended to prevent infectious complications in patients with necrotizing pancreatitis. Although the efficacy of the intravenous administration of protease inhibitors is still a matter of controversy, there is a consensus in Japan that a large dose of a synthetic protease inhibitor should be given to patients with severe acute pancreatitis in order to prevent organ failure and other complications. Enteral feeding is superior to parenteral nutrition when it comes to the nutritional support of patients with severe acute pancreatitis. The JPN Guidelines recommend, as optional measures, blood purification therapy and continuous regional arterial infusion of a protease inhibitor and antibiotics, depending on the patient's condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.