Evidence map›Paper›PMID 16462423›Full record

ReviewClinical orthopaedics and related research2006

Mineral changes in osteoporosis: a review.

Dan Faibish, Susan M Ott, Adele L Boskey

Open access · greenAbstract readReview
In one paragraph

Review in Clinical orthopaedics and related research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 152 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Protective effect of3 Biotech · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
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  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Biodegradable Magnesium-Based Implants in Orthopedics-A General Review and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dan FaibishMusculoskeletal Integrity Program, Hospital for Special Surgery, New York, NY 10021, USA.
Susan M Ott
Adele L Boskey
Hospital for Special Surgery · USUniversity of Washington · US

Funding

FT-IR MICROSCOPY OF MINERAL STRUCTURE IN OSTEOPOROSISR01AR041325 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI GOLDRING, MARY B · 1993 to 2017
$9.2M
TRABECULAR BONE ADAPTATION TO MECHANICAL LOADINGP30AR046121 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI MYERS, ELIZABETH R. · 1999 to 2010
$5.5M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR012538 · NCRR · HOSPITAL FOR SPECIAL SURGERY · PI BOSKEY, ADELE L · 1997 to 1997
–
NCRR NIH HHS C06 RR012538NIAMS NIH HHS AR043125NIAMS NIH HHS AR046121NIAMS NIH HHS P30 AR046121NIAMS NIH HHS R01 AR041325
6 · The paper itself

Abstract

Bone mineral composition, crystallinity, and bone mineral content of osteoporotic patients are different from those of normal subjects. We review the evidence that these mineralization parameters contribute to the strength (fracture resistance) of bone and the methods that have been used to examine them. A specific example is provided from analysis of biopsies from the Multiple Outcomes in Raloxifene Evaluation trial. For the analyses, randomly selected biopsies from placebo, low-dose, and high-dose groups (n = 5 per group) obtained at time zero and 2 years after treatment were examined by infrared imaging spectroscopy. In all cases, comparable increases in mineral content were found, but there were no significant variations in mineral crystallinity.

Indexed as

AnimalsBiopsyBone and BonesBone DensityHumansMineralsOsteoporosisSpectrum AnalysisMinerals

Identifiers

PMID16462423
PMCPMC1459416
OpenAlexW2039173239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.