Evidence map›Paper›PMID 16461998›Full record

ReviewImmunologic research2005

Regulatory T cell-mediated transplantation tolerance.

Ankit Bharat, Ryan Courtney Fields, T Mohanakumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Alloimmunity and autoimmunity in chronic rejection.Current opinion in organ transplantation · 2010
    Review
  11. Characterization of virus-specific T-cell immunity in liver allograft recipients with HCV-induced cirrhosis.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2008
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ankit BharatDepartment of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.
Ryan Courtney Fields
T Mohanakumar
Washington University in St. Louis · US

Funding

PATHOGENESIS OF POST-TRANSPLANT BRONCHIOLITIS OBLITERANSR01HL066452 · NHLBI · WASHINGTON UNIVERSITY · PI MOHANAKUMAR, THALACHALLOUR · 2001 to 2004
$1.2M
Pathogenesis of Post-Transplant Bronchiolitis ObliteransR56HL066452 · NHLBI · WASHINGTON UNIVERSITY · PI MOHANAKUMAR, THALACHALLOUR · 2008 to 2008
$380k
VERSATILE MULTIWAVELENGTH FLUOROMETERR43HL056543 · NHLBI · C AND L INSTRUMENTS, INC. · PI WANG, LI · 1995 to 1995
–
VERSATILE MULTIWAVELENGTH FLUOROMETERR44HL056543 · NHLBI · C AND L INSTRUMENTS, INC. · PI XIA, WEISHAN R · 1997 to 1998
–
NHLBI NIH HHS HL56543NHLBI NIH HHS HL66452
6 · The paper itself

Abstract

The existence of naturally occurring regulatory T cells in normal hosts and their pivotal role in maintaining both auto- and allo-tolerance have direct implications on the therapy of autoimmune disorders and for achieving immunosuppression-free allotransplantation. Among the various forms of regulatory T cells described, CD4(+)CD25(+) T cells have emerged as one of the most potent tolerogenic subsets. In this review, we discuss the molecular basis of development and function of these regulatory T cells and their potential role in the context of chronic lung allograft rejection.

Indexed as

AnimalsBronchiolitis ObliteransCD4 AntigensGraft RejectionHumansReceptors, Interleukin-2T-Lymphocytes, RegulatoryT-Lymphocyte SubsetsTransplantation ToleranceCD4 AntigensReceptors, Interleukin-2

Identifiers

PMID16461998
OpenAlexW2078480086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.