ArticleJournal of clinical microbiology2006
Multilocus microsatellite typing as a new tool for discrimination of Leishmania infantum MON-1 strains.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identification of infection by Leishmania spp. in wild and domestic animals in Brazil: a systematic review with meta-analysis (2001-2021).Parasitology research · 2023Pooled it
- Genetic Diversity and Population Structure ofPathogens (Basel, Switzerland) · 2023Article
- Article
- Microsatellite based molecular epidemiology of Leishmania infantum from re-emerging foci of visceral leishmaniasis in Armenia and pilot risk assessment by ecological niche modeling.PLoS neglected tropical diseases · 2021Article
- Genetic tools discriminate strains of Leishmania infantum isolated from humans and dogs in Sicily, Italy.PLoS neglected tropical diseases · 2020Article
- Occurrence of multiple genotype infection caused by Leishmania infantum in naturally infected dogs.PLoS neglected tropical diseases · 2020Article
- Dispersion of Leishmania (Leishmania) infantum in central-southern Brazil: Evidence from an integrative approach.PLoS neglected tropical diseases · 2019Article
- Analysis of genetic polymorphisms and tropism in East African Leishmania donovani by Amplified Fragment Length Polymorphism and kDNA minicircle sequencing.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018Article
- Multilocus microsatellite typing (MLMT) reveals host-related population structure in Leishmania infantum from northeastern Italy.PLoS neglected tropical diseases · 2018Article
- Genetic polymorphism in Leishmania infantum isolates from human and animals determined by nagt PCR-RFLP.Infectious diseases of poverty · 2018Article
- Population Structure ofBioMed research international · 2018Article
- Variability of Cutaneous Leishmaniasis Lesions Is Not Associated with Genetic Diversity ofThe American journal of tropical medicine and hygiene · 2017Article
- Leishmania infantum Genetic Diversity and Lutzomyia longipalpis Mitochondrial Haplotypes in Brazil.BioMed research international · 2016Article
- Genetic Diversity and Population Structure of Leishmania infantum from Southeastern France: Evaluation Using Multi-Locus Microsatellite Typing.PLoS neglected tropical diseases · 2016Article
- Multilocus microsatellite typing of Leishmania infantum isolates in monitored Leishmania/HIV coinfected patients.Parasites & vectors · 2015Article
- A narrative review of visceral leishmaniasis in Armenia, Azerbaijan, Georgia, Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, Uzbekistan, the Crimean Peninsula and Southern Russia.Parasites & vectors · 2015Review
- Genetic homogeneity among Leishmania (Leishmania) infantum isolates from dog and human samples in Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil.Parasites & vectors · 2015Article
- Multilocus microsatellite typing of Leishmania and clinical applications: a review.Parasite (Paris, France) · 2015Review
- Multilocus sequence and microsatellite identification of intra-specific hybrids and ancestor-like donors among natural Ethiopian isolates of Leishmania donovani.International journal for parasitology · 2014Article
- LeishMicrosatDB: open source database of repeat sequences detected in six fully sequenced Leishmania genomes.Database : the journal of biological databases and curation · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Leishmania donovani complex, which consists of L. donovani, L. infantum-L. chagasi, and L. archibaldi, is responsible for visceral manifestations of leishmaniasis. Multilocus enzyme electrophoresis is the standard method for the characterization and identification of strains of Leishmania. For L. infantum, the predominance of zymodeme MON-1 significantly reduces the discriminative power of this approach. In the present study, we developed 17 independent polymorphic microsatellite markers for the typing of strains of L. infantum, with the main emphasis on zymodeme MON-1. The discriminative powers of 11 markers selected from among these markers were tested by using a panel of 63 isolates of the L. donovani complex. Unique multilocus genotypes were observed for the strains analyzed, with only three exceptions. Model-based and distance-based analyses of the data set showed comparable results. It was possible to discriminate between L. donovani sensu stricto, a non-MON-1 group of L. infantum isolates, and a MON-1 group of L. infantum isolates. Within MON-1, three clusters with geographical correlations became apparent. The frequency of heterozygosity in the alleles analyzed varied extremely between the different groups of isolates. The main clusters described are not consistent with species definitions based on isoenzyme analysis but confirm the results of former PCR-based investigations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.