ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2006
Neuromechanics of coordination during swallowing in Aplysia californica.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed, 39 citations in OpenAlex.
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- Identified neurons B4/B5 function as sensory neurons, motor neurons, and interneurons inJournal of neurophysiology · 2025Article
- Cellular mechanisms underlying carry-over effects after magnetic stimulation.Scientific reports · 2024Article
- Cellular mechanisms underlying state-dependent neural inhibition with magnetic stimulation.Scientific reports · 2022Article
- Somatic inhibition by microscopic magnetic stimulation.Scientific reports · 2021Article
- Control for multifunctionality: bioinspired control based on feeding in Aplysia californica.Biological cybernetics · 2020Article
- Axonal blockage with microscopic magnetic stimulation.Scientific reports · 2020Article
- Soft-surface grasping: radular opening inThe Journal of experimental biology · 2019Article
- Successful and unsuccessful attempts to swallow in a reducedLearning & memory (Cold Spring Harbor, N.Y.) · 2019Article
- Flexible microelectrode array for interfacing with the surface of neural ganglia.Journal of neural engineering · 2018Article
- Preparing the periphery for a subsequent behavior: motor neuronal activity during biting generates little force but prepares a retractor muscle to generate larger forces during swallowing in Aplysia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Motor neuronal activity varies least among individuals when it matters most for behavior.Journal of neurophysiology · 2015Article
- Differential activation of an identified motor neuron and neuromodulation provide Aplysia's retractor muscle an additional function.Journal of neurophysiology · 2014Article
- Stability in a frontal plane model of balance requires coupled changes to postural configuration and neural feedback control.Journal of neurophysiology · 2011Article
- The brain in its body: motor control and sensing in a biomechanical context.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Review
- Training with inedible food in Aplysia causes expression of C/EBP in the buccal but not cerebral ganglion.Learning & memory (Cold Spring Harbor, N.Y.) · 2008Article
- Predicting adaptive behavior in the environment from central nervous system dynamics.PloS one · 2008Article
- Neuromechanics of muscle synergies for posture and movement.Current opinion in neurobiology · 2007Review
- State dependence of spike timing and neuronal function in a motor pattern generating network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Bernstein (1967) hypothesized that preparation of the periphery was crucial for correct responses to motor output. To test this hypothesis in a behaving animal, we examined the roles of two identified motor neurons, B7 and B8, which contribute to feeding behavior in the marine mollusk Aplysia californica. Neuron B7 innervates a hinge muscle and has no overt behavioral effect during smaller-amplitude (type A) swallows, because the hinge muscle is too short to exert force. Neuron B8 activates a muscle (I4) that acts solely to grasp material during type A swallows. During larger-amplitude (type B) swallows, the behavioral actions of both motor neurons change, because the larger-amplitude anterior movement of the grasper sets up the periphery to respond differently to motor outputs. The larger anterior movement stretches the hinge muscle, so that activating neuron B7 mediates the initial retraction phase of swallowing. The changed position of the I4 muscle allows neuron B8 not only to induce grasping but also to pull material into the buccal cavity, contributing to retraction. Thus, larger-amplitude swallows are associated with the expression of two new degrees of freedom (use of the hinge to retract and use of the grasper to retract) that are essential for mediating type B swallows. These results provide a direct demonstration of Bernstein's hypothesis that properly positioning the periphery can be crucial for its ability to correctly respond to motor output and also demonstrate that biomechanical context can alter the functions of identified motor neurons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.