ArticleEuropean journal of epidemiology2006
Is inflammation a causal chain between low socioeconomic status and type 2 diabetes? Results from the KORA Survey 2000.
Article in European journal of epidemiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Socioeconomic and racial/ethnic differentials of C-reactive protein levels: a systematic review of population-based studies.BMC public health · 2007Pooled it
- Inflammation a possible link between economical stress and coronary heart disease.European journal of epidemiology · 2008Trial
- Income and risk of type 2 diabetes incidence varied associations according to obesity status: a nationwide study.BMC public health · 2026Article
- Social determinants of inflammatory markers linking depression and type 2 diabetes among women: A scoping review.Journal of psychosomatic research · 2024Article
- Association of Sustained Low or High Income and Income Changes With Risk of Incident Type 2 Diabetes Among Individuals Aged 30 to 64 Years.JAMA network open · 2023Article
- Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes: a narrative review with emphasis on data from Europe.BMC endocrine disorders · 2020Review
- Short-term Effect of Ambient Air Pollution on Emergency Department Visits for Diabetic Coma in Seoul, Korea.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2018Article
- Childhood victimization and inflammation in young adulthood: A genetically sensitive cohort study.Brain, behavior, and immunity · 2018Article
- The role of childhood social position in adult type 2 diabetes: evidence from the English Longitudinal Study of Ageing.BMC public health · 2014Article
- The social patterns of a biological risk factor for disease: race, gender, socioeconomic position, and C-reactive protein.The journals of gerontology. Series B, Psychological sciences and social sciences · 2012Article
- Socioeconomic status and incident type 2 diabetes mellitus: data from the Women's Health Study.PloS one · 2011Article
- Psychological perspectives on pathways linking socioeconomic status and physical health.Annual review of psychology · 2011Review
- Health behaviours, socioeconomic status and diabetes incidence: the Australian Diabetes Obesity and Lifestyle Study (AusDiab).Diabetologia · 2010Article
- Systemic inflammation and the metabolic syndrome among middle-aged community volunteers.Metabolism: clinical and experimental · 2010Article
- To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers.Brain, behavior, and immunity · 2009Article
- Association of socioeconomic status with inflammation markers in black and white men and women in the Coronary Artery Risk Development in Young Adults (CARDIA) study.Social science & medicine (1982) · 2009Article
- Sex and gender in psychoneuroimmunology research: past, present and future.Brain, behavior, and immunity · 2009Review
- Stroke disparities in older Americans: is wealth a more powerful indicator of risk than income and education?Stroke · 2008Article
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8 authors.
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Abstract
Low socioeconomic status (SES) is associated with type 2 diabetes. Inflammatory markers like C-reactive protein (CRP) are predictive of diabetes. It is unclear, whether inflammation may be a mechanism linking low SES to type 2 diabetes. In the population-based KORA Survey 2000, 766 men and 710 women aged 55 to 74 years were randomly selected in the Augsburg region (Southern Germany). An index for SES was defined using education, occupation, and income. In women but not in men, increased CRP concentrations were found with lower SES (p<0.01). This significant trend was no longer observed after adjusting for BMI and waist circumference (p=0.23). Low SES was significantly associated with the age-adjusted odds of having type 2 diabetes both in men (OR; 95%CI: 1.35; 1.14-1.60) and in women (2.01; 1.37-2.96). The risk of having diabetes associated with low SES was only slightly changed after adjusting for CRP, which was itself significantly related to diabetes. In multivariate analyses, adjusting for age, obesity, physical activity, smoking, alcohol intake, and CRP, low SES yielded only a borderline statistical significance in women (p=0.07), whereas no significant association with diabetes remained in men (p=0.14). After CRP was dropped from the full model, there was no change in the OR obtained for low SES (men: 1.30; 0.92-1.83; women: 1.54; 0.97-2.45). Low SES was not related to prediabetes (IFG, IGT), whereas CRP was significantly associated with diabetes precursors. In conclusion, inflammation appears not to play a major role linking low SES and type 2 diabetes in the elderly population.
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