Evidence map›Paper›PMID 16450072›Full record

ArticleCurrent microbiology2006

Fluoroquinolone resistance linked to both gyrA and parC mutations in the quinolone resistance-determining region of Shigella dysenteriae type 1.

Kaisar A Talukder, Bijay K Khajanchi, Mohammad A Islam, Zhahirul Islam, Dilip K Dutta, Mustafizur Rahman, Haruo Watanabe, Gopinath B Nair, David A Sack

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Current microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Article
  7. Article
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  12. Options for treating resistant Shigella species infections in children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaisar A TalukderICDDR, B: Centre for Health and Population Research, GPO Box-128, Dhaka, 1000, Bangladesh. kaisar@icddrb.org
Bijay K Khajanchi
Mohammad A Islam
Zhahirul Islam
Dilip K Dutta
Mustafizur Rahman
Haruo Watanabe
Gopinath B Nair
David A Sack

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined the quinolone resistance-determining region (QRDR) of gyrA, gyrB, and parC of recently isolated fluoroquinolone-resistant S. dysenteriae type 1 strains from south Asia and compared data with fluoroquinolone-susceptible strains associated with previous epidemics of 1978, 1984, and 1994. In fluoroquinolone-resistant strains, double mutations (Ser83-->Leu, Asp87-->Asn or Gly) and a single mutation (Ser80-->Ile) were detected in the QRDRs of gyrA and parC, respectively.

Indexed as

Anti-Bacterial AgentsAsia, SoutheasternDNA GyraseDNA Topoisomerase IVDrug Resistance, BacterialDysentery, BacillaryFluoroquinolonesHumansMicrobial Sensitivity TestsMolecular Sequence DataMutationQuinolonesShigella dysenteriaeAnti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVFluoroquinolonesQuinolones

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.